Wyszukano: Copper+di-ammonium+EDTA

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wodorofosforan diamonu, Sigma-Aldrich®

Producent: Merck

Opis: wodorofosforan diamonu, Sigma-Aldrich®

Octan miedzi(II), Sigma-Aldrich®

Producent: Merck

Opis: Octan miedzi(II), Sigma-Aldrich®

VWR® Powder Packs do oznaczania miedzi, odczynniki do fotometrów

Producent: VWR Chemicals

Opis: VWR® powder pack reagents are designed to be used on laboratory and portable photometers with 16 mm cell capability. No calibration data is necessary. The pillows, individually sealed in aluminium foil packs, are unaffected by ambient conditions and contain pre-measured powder reagents for accuracy, convenience and great solubility.

Certyfikaty

wodorofosforan diamonu 99% for biochemistry

Producent: Thermo Fisher Scientific

Opis: wodorofosforan diamonu 99% for biochemistry

MSDS

molibdenian amonowy 4% (w/v) roztwór wodny

Producent: Thermo Fisher Scientific

Opis: molibdenian amonowy 4% (w/v) in aqueous solution

MSDS Certyfikaty

Octan miedzi(II) hydrat 98.0-102.0% ACS

Producent: Thermo Fisher Scientific

Opis: Octan miedzi(II) hydrat 98.0-102.0% ACS

MSDS Certyfikaty

Human recombinant S100 calcium binding A12 (from E. coli)

Numer katalogowy: (PRSI91-588)

Producent: ProSci Inc.

Opis: Human EN-RAGE belongs to the S100/calgranulin superfamily. There are at least 21 different S100 proteins and the protein is 100% soluble in ammonium sulfate at neutral pH. S100 proteins play a role in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.Human EN-RAGE is characterized by two EF-hand calcium-binding motifs, zinc- and copper-binding protein.S100A12 is a disulfide-linked homodimer and the interface between the two subunits is composed mostly of hydrophobic residues.Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. EN-RAGE acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. It also acts as a monocyte and mast cell chemoattractant. Moreover, it can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. It can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn2+from their active sites.

j.m.: 1 * 50 µG

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