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Numer katalogowy: (ABCAAB238670-100)
Producent: Abcam
Opis: Mouse monoclonal [1F8] to ENPP2/ATX - BSA and Azide free.
j.m.: 1 * 100 µG


Numer katalogowy: (118-1702)
Producent: Plum Safety
Opis: Available as either an open station or closed and dust-proof wall box containing 2×500 ml plum eyewash bottles.
j.m.: 1 * 1 SZT


Numer katalogowy: (USBIB0175-05D)
Producent: US Biological
Opis: Anti-BAX Mouse Monoclonal Antibody [clone: 6A7]
j.m.: 1 * 50 µG


Numer katalogowy: (DUEH2.233.04)
Producent: DUPERTHAL
Opis: Storage cabinet, Red-box, for safety storage of documents
j.m.: 1 * 1 SZT


Numer katalogowy: (ABCAAB236312-100)
Producent: Abcam
Opis: Rabbit monoclonal [BTN/2032R] to Biotin - BSA and Azide free.
j.m.: 1 * 100 µG


Numer katalogowy: (BOSSBS-2765R-A750)
Producent: Bioss
Opis: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
j.m.: 1 * 100 µl


Producent: Biotium
Opis: Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Producent: Biotium
Opis: Recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Numer katalogowy: (USBI124039)
Producent: US Biological
Opis: Anti-BTD Mouse Monoclonal Antibody [clone: 3B10-2B3]
j.m.: 1 * 100 µG


Numer katalogowy: (BOSSBS-0127R-A555)
Producent: Bioss
Opis: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-11813R-FITC)
Producent: Bioss
Opis: Biotin, also known as vitamin B7, is an essential water-soluble vitamin that is a cofactor in glucogenesis and in the metabolism of fatty acids and leucine. Biotinidase is a 523 amino acid enzyme that catalyzes the hydrolysis of biocytin to biotin and lysine. Secreted into extracellular space, biotinidase is expressed in liver, heart, placenta, brain, skeletal muscle, pancreas and kidney. Biotinidase contains one carbon-nitrogen hydrolase domain, which is involved in the reduction of organic nitrogen compounds and ammonia production. Defects in the gene encoding biotinidase are the cause of biotinidase deficiency, which is characterized by skin rash, ataxia, seizures, hearing loss, hypotonia and optic atrophy. These symptoms are due to the individual’s inability to reutilize biotin and can, therefore, typically be treated with the addition of free biotin.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-2765R-A647)
Producent: Bioss
Opis: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-2752R-A488)
Producent: Bioss
Opis: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-12864R-A350)
Producent: Bioss
Opis: Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.
j.m.: 1 * 100 µl


Producent: ELTEN
Opis: Lightweight and comfortable ESD safety ankle boots made from cowhide leather, GORE-TEX® lining, reflective materials, a full padded bellows tongue and a dual density PU-PU sole ERGO-ACTIVE 2.

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Numer katalogowy: (USBIB2187-60C-HRP)
Producent: US Biological
Opis: Anti-BMX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
j.m.: 1 * 200 µl


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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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