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Product Image-AATB21054

BTC, AM ≥95%

Numer katalogowy: (AATB21054)
Producent: AAT BIOQUEST
Opis: This cell-permeant coumarin Ca2+ indicator BTC, AM exhibits a shift in excitation maximum from about 480 nm to 400 nm upon binding Ca2+, enabling ratiometric calcium measurements.
j.m.: 1 * 1 mg
Image Unavailable-TENATE21928

Stojaki na goblety do zamrażarek na ciekły azot, Tenak

Producent: TENAK
Opis: Goblet racks are used for cryogenic LN2 freezer and made of stainless steel.

Product Image-USBI030802-HRP

Anti-BAX Mouse Monoclonal Antibody (HRP (Horseradish Peroxidase)) [clone: 557CT5.2.1]

Numer katalogowy: (USBI030802-HRP)
Producent: US Biological
Opis: Anti-BAX Mouse Monoclonal Antibody (HRP (Horseradish Peroxidase)) [clone: 557CT5.2.1]
j.m.: 1 * 200 µl
Product Image-USBI032435-PE

Anti-BAX Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Numer katalogowy: (USBI032435-PE)
Producent: US Biological
Opis: Anti-BAX Rabbit Polyclonal Antibody (PE (Phycoerythrin))
j.m.: 1 * 200 µl
Product Image-USBI032435-HRP

Anti-BAX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (USBI032435-HRP)
Producent: US Biological
Opis: Anti-BAX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
j.m.: 1 * 200 µl
Product Image-USBI032434-PE

Anti-BAX Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Numer katalogowy: (USBI032434-PE)
Producent: US Biological
Opis: Anti-BAX Rabbit Polyclonal Antibody (PE (Phycoerythrin))
j.m.: 1 * 200 µl
Product Image-ZVGA16515

Chusteczki do twarzy i powierzchni, zetBox®

Numer katalogowy: (ZVGA16515)
Producent: Zellstoff-Vertriebs-GmbH & Co. KG
Opis: These double-layered laboratory and facial tissues from zetBox® are highly absorbent and ultra-soft. Perfect for sensitive application areas.
j.m.: 1 * 4.500 SZT
Image Unavailable-AVIVARP39409_P050

Anti-BBX Rabbit Polyclonal Antibody

Numer katalogowy: (AVIVARP39409_P050)
Producent: Aviva Systems Biology
Opis: Anti-BBX Rabbit Polyclonal Antibody
j.m.: 1 * 50 µG
Product Image-AVIVARP33173_P050

Anti-BBX Rabbit Polyclonal Antibody

Numer katalogowy: (AVIVARP33173_P050)
Producent: Aviva Systems Biology
Opis: Anti-BBX Rabbit Polyclonal Antibody
j.m.: 1 * 50 µG
Product Image-ABGEAP20669C

Anti-BTK Rabbit Polyclonal Antibody

Numer katalogowy: (ABGEAP20669C)
Producent: Abgent
Opis: Anti-BTK Rabbit Polyclonal Antibody
j.m.: 1 * 400 µl
Image Unavailable-ENZOADIAAS040F

Anti-BAX Rabbit Polyclonal Antibody

Producent: ENZO LIFE SCIENCES
Opis: Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade.

Image Unavailable-BWRLBS6537

Anti-BTK Rabbit Polyclonal Antibody

Numer katalogowy: (BWRLBS6537)
Producent: Bioworld Technology
Opis: Recombinant full length Human BTK.
j.m.: 1 * 100 µG
Image Unavailable-BOSSBS-12901R

Anti-BTK Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-12901R)
Producent: Bioss
Opis: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.
j.m.: 1 * 100 µl
Product Image-BOSSBS-3055R

Anti-BTK Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-3055R)
Producent: Bioss
Opis: Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molecule in regulating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription regulation. Induces the activity of NF-kappa-B, which is involved in regulating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind regulatory enhancer elements to modulate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the regulation of apoptosis.
j.m.: 1 * 100 µl
Product Image-ABCAAB52192-100

Anti-BTK Rabbit Polyclonal Antibody

Numer katalogowy: (ABCAAB52192-100)
Producent: Abcam
Opis: Rabbit polyclonal to BTK (phospho Y551).
j.m.: 1 * 100 µG
Product Image-ABCAAB262929-100

Anti-Bax Rabbit Polyclonal Antibody

Numer katalogowy: (ABCAAB262929-100)
Producent: Abcam
Opis: Rabbit polyclonal to Bax.
j.m.: 1 * 100 µl
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
Do zakupu tego produktu może być potrzebna dodatkowa dokumentacja. Przedstawiciel VWR skontaktuje się z Tobą w razie potrzeby.
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Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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