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Image Unavailable-BOSSBS-6634R-A680

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-6634R-A680)
Producent: Bioss
Opis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-FITC

Anti-XPC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numer katalogowy: (BOSSBS-6634R-FITC)
Producent: Bioss
Opis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
j.m.: 1 * 100 µl
Product Image-228-0376

Versilic™ Tubings, Silicone

Producent: Saint Gobain Life Sciences
Opis: This tubing meets European Pharmacopoeia requirements for silicone elastomer for closures and tubing, USP Class VI biological tests and ISO 10993 biocompatibility (systemic toxicity, irritation, sensitisation, citotoxicity, hemocompatibility and Ames test).

Image Unavailable-AATB3112

mFluor™ UV 460 Biotin conjugate

Numer katalogowy: (AATB3112)
Producent: AAT BIOQUEST
Opis: mFluor™ UV 460 Biotin Conjugate contains mFluor™ UV 460 fluorophore that is well excited by the common 350 nm laser.
j.m.: 1 * 1 mg

New Product


Image Unavailable-UVPA34-0056-02

Akcesoria do lamp wielopromieniowych UV

Producent: UVP ULTRA VIOLET PRODUCTS
Opis: UV lamp, Replacement UV tube for MRL-58, longwave, filtered BLB, 8 W output, 365 nm wavelength

Image Unavailable-BOSSBS-0553R-A750

Anti-Collagen 6 alpha 1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numer katalogowy: (BOSSBS-0553R-A750)
Producent: Bioss
Opis: Collagen VI acts as a cell-binding protein.
j.m.: 1 * 100 µl
Product Image-UVPA90-0049-01

Fotochemiczne kwarcowe lampy UV,, Pen-Ray®

Numer katalogowy: (UVPA90-0049-01)
Producent: UVP ULTRA VIOLET PRODUCTS
Opis: UV lamp, Photochemical quartz lamp, lighted length of 63,5 mm, Pen-Ray®, 254 nm
j.m.: 1 * 1 SZT
Image Unavailable-BOSSBS-8324R-A555

Anti-SERPINB13 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numer katalogowy: (BOSSBS-8324R-A555)
Producent: Bioss
Opis: Headpin is a skin-specific, UV-repressible serine proteinase inhibitor (serpin) belonging to the ovalbumin serpin family. Headpin is abundant in the human keratinocyte cell line HaCaT, and in lesional keratinocytes from psoriatic skin. Headpin downregulation occurs in squamous cell carcinoma of the oral cavity and in squamous cell carcinoma cell lines of the head and neck.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-8324R-A488

Anti-SERPINB13 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-8324R-A488)
Producent: Bioss
Opis: Headpin is a skin-specific, UV-repressible serine proteinase inhibitor (serpin) belonging to the ovalbumin serpin family. Headpin is abundant in the human keratinocyte cell line HaCaT, and in lesional keratinocytes from psoriatic skin. Headpin downregulation occurs in squamous cell carcinoma of the oral cavity and in squamous cell carcinoma cell lines of the head and neck.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-8324R-CY5

Anti-SERPINB13 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-8324R-CY5)
Producent: Bioss
Opis: Headpin is a skin-specific, UV-repressible serine proteinase inhibitor (serpin) belonging to the ovalbumin serpin family. Headpin is abundant in the human keratinocyte cell line HaCaT, and in lesional keratinocytes from psoriatic skin. Headpin downregulation occurs in squamous cell carcinoma of the oral cavity and in squamous cell carcinoma cell lines of the head and neck.
j.m.: 1 * 100 µl
Product Image-734-2851

VWR® Zestaw butelkowy, PETG, sterylny, jednorazowy

Producent: VWR Collection
Opis: Sterile PETG containers, with weldable tubings, provide the maximum amount of flexibility and reliability. These vessels are assembled in an ISO Class 7 cleanroom and are manufactured from USP Class VI materials. They come in a comprehensive size selection with tubing that is completely weldable/sealable.

Certyfikaty

Image Unavailable-BOSSBS-0527R-A680

Anti-CD10 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-0527R-A680)
Producent: Bioss
Opis: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 3 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibres.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-0527R-A647

Anti-MME Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-0527R-A647)
Producent: Bioss
Opis: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 3 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-0527R-PE

Anti-MME Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Numer katalogowy: (BOSSBS-0527R-PE)
Producent: Bioss
Opis: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 3 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-0527R-A350

Anti-MME Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-0527R-A350)
Producent: Bioss
Opis: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 3 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
j.m.: 1 * 100 µl
Product Image-USBI043695

Anti-UVRAG Rabbit Polyclonal Antibody

Numer katalogowy: (USBI043695)
Producent: US Biological
Opis: Anti-UVRAG Rabbit Polyclonal Antibody
j.m.: 1 * 200 µl
Cena wymaga potwierdzenia u dostawcy
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
Do zakupu tego produktu może być potrzebna dodatkowa dokumentacja. Przedstawiciel VWR skontaktuje się z Tobą w razie potrzeby.
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Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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