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Producent: Biotium
Opis: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Producent: Biotium
Opis: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Producent: Biotium
Opis: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Producent: Binder
Opis: Qualification documents. Digital IQ/OQ documents inside folder - supporting documents for validation performed by customers, consisting of: IQ/OQ checklists includes calibration guide and comprehensive unit documentation; parameters: temperature, CO₂, O₂, pressure, depending on unit, Do: UF V

Producent: Thermo Fisher Scientific
Opis: Heratherm™ CO₂ incubators offer exceptional environmental control in a hassle-free chamber that is easy to program and use.

New Product

Producent: Tonbo Biosciences
Opis: The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.

Numer katalogowy: (BOSSBS-7830R)
Producent: Bioss
Opis: Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-9074R-CY5.5)
Producent: Bioss
Opis: Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-9074R-CY7)
Producent: Bioss
Opis: Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.
j.m.: 1 * 100 µl


Numer katalogowy: (40-9985-U100)
Producent: Tonbo Biosciences
Opis: The J43.1 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein which can co-regulate T cell antigen receptor signaling and therefore modulate T cell activation. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells. PD-1 is a member of a family of receptors including CD28 and CTLA-4 (CD152), which interact with 'B7' ligands to provide a balance of co-stimulatory /co-inhibitory signaling important in T cell activation, tolerance, and autoimmunity.
j.m.: 1 * 100 µG


Producent: Tonbo Biosciences
Opis: The 37.51 antibody reacts with mouse CD28, a 45 kDa glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction/co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of co-stimulatory receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

Producent: Apollo Scientific
Opis: Improves low temperature performance & chemical resistance when used as a co-polymer to VDF &/or PTFE.

Numer katalogowy: (BOSSBS-2463R)
Producent: Bioss
Opis: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production (By similarity).
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-1484R-CY5)
Producent: Bioss
Opis: catalyses the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
j.m.: 1 * 100 µl


Producent: Thermo Fisher Scientific
Opis: Cd, Co, Cr, Cu, Fe, Mn, Ni, V, Zn @ 100 µg/ml
Producent: TriLink BioTechnologies
Opis: TriLink's patented CleanCap® Reagent AG (3' OMe) is a co-transcriptional capping reagent for <em>in vitro</em> transcription of 5' capped mRNA resulting in a Cap 1 structure with >95% capping efficiency.

New Product

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Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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