Wyszukano: ENZO LIFE SCIENCES

Numer katalogowy: (ENZOADIMSA150E)

Producent: ENZO LIFE SCIENCES

Opis: Thioredoxins act as antioxidants by reducing the proteins by cysteine thiol-disulfide exchange. Several plasmid expression vectors have been constructed that direct the synthesis of foreign polypeptides in E. coli as fusions with C-terminal Thioredoxin (TrxA) to offer soluble expression of normally insoluble or difficult to express proteins such as cytokines and growth factors.

j.m.: 1 * 100 µG

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Numer katalogowy: (ENZOADIKASMA013E)

Producent: ENZO LIFE SCIENCES

Opis: MEKKs (Mitogen activated protein kinase kinase kinases) are serine-threonine kinases that act as the first tier of cellular MAP kinase pathways by activation of MAP/ERK kinases, or MEKs. Many enzymes with MEKK activity have been identified, including MEKK1-4, Raf, MLK3, TAK, and DLK. MEKKs generally display little similarity outside of their catalytic kinase domains. MEKK1-4 are nearly 50% identical within their catalytic domains, and are known to regulate Erk, Jnk, and p38 MAP kinase pathways. MEKK2 and MEKK3 bind MEK5 via conserved PB1 domains, leading to downstream activation of Erk5.

j.m.: 1 * 100 µl

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Numer katalogowy: (ENZOADISPA885J)

Producent: ENZO LIFE SCIENCES

Opis: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

j.m.: 1 * 1 mg

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Producent: ENZO LIFE SCIENCES

Opis: Hsp65 is a member of the Hsp60 family of heat shock proteins isolated from Mycobacterium bovis BCG. Hsp65 from M. bovis is identical to that of M. tuberculosis, and similar to that of M. leprae, two highly pathogenic strains of mycobacterium. Hsp65 is the immunodominant antigen during mycobacterial infection and vaccination, and has been linked to the development of autoimmune adjuvant arthritis in rats.

Producent: ENZO LIFE SCIENCES

Opis: HSFs (Heat Shock family of transcription factors), which consists of HSF 1-4, bind to highly conserved Heat shock elements (HSEs) in the promoter regions of heat shock genes, ultimately regulating the expression of Heat shock proteins (Hsps). On exposure to heat shock and other stresses, HSF1 localizes within seconds to discrete nuclear granules and on recovery from stress, HSF1 rapidly dissipates from the stress granules to a diffuse nucleoplasmic distribution.

Producent: ENZO LIFE SCIENCES

Opis: The mammalian PDI (Protein disulfide-isomerase) family encompasses several highly divergent proteins which are involved in the processing and maturation of secretory proteins in the endoplasmic reticulum by catalyzing the rearrangement of disulfide bonds.

Producent: ENZO LIFE SCIENCES

Opis: Produced in <i>E. coli</i>. Human αB-Crystallin is fused at the N-terminus to a His-tag.

Producent: ENZO LIFE SCIENCES

Opis: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members.

Producent: ENZO LIFE SCIENCES

Opis: Produced in <i>E. coli</i>.

Producent: ENZO LIFE SCIENCES

Opis: Produced in <i>E. coli</i>.

Numer katalogowy: (ENZOADIVAMPS002E)

Producent: ENZO LIFE SCIENCES

Opis: Postsynaptic density protein 95 kDa (PSD-95), also known as Synapse associated protein 90 kDa (SAP90), is a brain specific protein that is highly similar to the Drosophila dlg tumor suppressor protein. PSD-95 is a member of membrane associated proteins that are localized beneath the postsynaptic membrane of synapses in the CNS. PSD-95 interacts with NMDA receptor and Shaker-type K+ channels and contributes to their clustering and localization at the synaptic spines in hippocampal neurons and the pinceau terminal of cerebellar basket cells, respectively.

j.m.: 1 * 100 µG

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Numer katalogowy: (ENZOALX210192R100)

Producent: ENZO LIFE SCIENCES

Opis: Host: Rabbit

j.m.: 1 * 100 µl

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Producent: ENZO LIFE SCIENCES

Opis: Produced in <i>E. coli.</i> Non-glycosylated protein, containing 147 amino acids.

Numer katalogowy: (ENZOALX210130C100)

Producent: ENZO LIFE SCIENCES

Opis: Host: Rabbit

j.m.: 1 * 100 µG

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Numer katalogowy: (ENZOALX210132C100)

Producent: ENZO LIFE SCIENCES

Opis: Host: Rabbit

j.m.: 1 * 100 µG

Wyprzedaż

Producent: ENZO LIFE SCIENCES

Opis: Produced in <i>E. coli</i>. <i>E. coli</i> DnaJ is fused at the N-terminus to a His-tag.