Wyszukano: ENZO LIFE SCIENCES

Numer katalogowy: (ENZOALX306031M001)

Producent: ENZO LIFE SCIENCES

Opis: Potent stimulator of NKT cells.

j.m.: 1 * 1 mg

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Producent: ENZO LIFE SCIENCES

Opis: Na+ channel blocker

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Numer katalogowy: (ENZOBMLNA1250010)

Producent: ENZO LIFE SCIENCES

Opis: Na⁺ channel activator.

j.m.: 1 * 10 mg

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Producent: ENZO LIFE SCIENCES

Opis: TrkA ligand

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Producent: ENZO LIFE SCIENCES

Opis: The 90 kDa molecular chaperone family includes 90 kDa heat shock protein Hsp90 and 94 kDa glucose-regulated protein grp94, both major molecular chaperones of the cytosol and the endoplasmic reticulum. Mammalian cells contain isoforms Hsp90 alpha and Hsp90 beta, encoded by separate genes. The amino acid sequences of human and yeast Hsp90 alpha are 85% and 90% homologous to those of Hsp90 beta, respectively. All known members of the Hsp90 protein family are highly conserved, especially in the N -terminal and C-terminal regions containing independent chaperone sites with different substrate specificity. These ubiquitous and highly conserved proteins account for 1-2% of all cellular proteins in most cells. Hsp90 functions as part of the cell

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Producent: ENZO LIFE SCIENCES

Opis: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

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Numer katalogowy: (ENZOBMLFR1170500)

Producent: ENZO LIFE SCIENCES

Opis: L-Buthionine-sulfoximine (BSO) induces oxidative stress in cells by irreversibly inhibiting γ-glutamylcysteine synthetase, an essential enzyme for the synthesis of glutathione.

j.m.: 1 * 500 mg

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Producent: ENZO LIFE SCIENCES

Opis: HMG-CoA reductase inhibitor

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Numer katalogowy: (ENZOBMLFR1130250)

Producent: ENZO LIFE SCIENCES

Opis: Potent iron chelator

j.m.: 1 * 250 mg

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Numer katalogowy: (ENZOBMLG1010050)

Producent: ENZO LIFE SCIENCES

Opis: <i>Bordetella pertussis</i> toxin (Islet-activating protein, PTX) from <i>Bordetella pertussis</i>, strain NCTC 10739. is a high purity toxin applicable to ELISA, antibody capture, cytotoxicity studies, LINE assay.

j.m.: 1 * 50 µG

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Numer katalogowy: (ENZOBMLFR1040100)

Producent: ENZO LIFE SCIENCES

Opis: Antioxidant. SIRT1 activator.

j.m.: 1 * 100 mg

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Numer katalogowy: (ENZOBMLFG60200100)

Producent: ENZO LIFE SCIENCES

Opis: Fibronectins are high molecular weight, disulphide-linked, dimeric cell adhesion glycoproteins found in basement membranes and in the interstitial connective tissue matrix. A single fibronectin gene is subject to alternative splicing in a cell-type-, development- and age-regulated manner which gives rise to multiple molecular forms. In addition to their prominent role in adhesion, fibronectins have been reported to mediate various aspects of cellular interaction, including migration during development and wound-healing, haemostasis, and the regulation of cell growth and differentiation. Cellular fibronectins (cFn) are found in low amounts in normal human plasma and tissues, but they are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas. In contrast, a soluble form of fibronectin produced by hepatocytes is readily detectable in plasma and becomes deposited in pericellular matrices and within tissues. This form of fibronectin, referred to as ‘plasma fibronectin’ (pFn), differs from cFn by the absence of an amino acid sequence, known as extra domain A1.

j.m.: 1 * 100 µl

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Numer katalogowy: (ENZOBMLG1170001)

Producent: ENZO LIFE SCIENCES

Opis: G protein activator.

j.m.: 1 * 1 mg

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Numer katalogowy: (ENZOBMLG1500050)

Producent: ENZO LIFE SCIENCES

Opis: <i>Clostridium difficile </i>toxin B from<i> Clostridium difficile</i>, strain VPI10463 is a high purity toxin applicable to ELISA, antibody capture, cytotoxicity studies and LINE assay.

j.m.: 1 * 50 µG

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Numer katalogowy: (ENZOALX802009R100)

Producent: ENZO LIFE SCIENCES

Opis: Host: Mouse, Isotype: IgG1

j.m.: 1 * 100 µl

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Numer katalogowy: (ENZOALX8010901)

Producent: ENZO LIFE SCIENCES

Opis: Host: Mouse, Isotype: IgM

j.m.: 1 * 1 Vial

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