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Image Unavailable-BOSSBS-6634R-HRP

Anti-XPC Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-6634R-HRP)
Producent: Bioss
Opis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
j.m.: 1 * 100 µl
Product Image-731-0750

Folia uszczelniajaca, niefluorescencyjna, Nunc™

Numer katalogowy: (731-0750)
Producent: Thermo Fisher Scientific
Opis: Folia winylowa z wrażliwym na ciśnienie klejem akrylowym. Folia do aplikowania na spód lub wierzch płytki, w celu ochrony próbek wrażliwych na światło.
j.m.: 1 * 50 SZT

Environmentally Preferable


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Udoskonalenia w zakresie lokalizacji zapasów magazynowych

Image Unavailable-ENTE202-122-01

Pneumatyczne zawory membranowe, Integra®

Producent: ENTEGRIS
Opis: Available compliant to SEMI Standard F57-0312, the specification for polymer components used in ultrapure water and liquid chemical distribution systems. Higher performance with greater back (outlet) pressure capability. All wetted parts are molded PFA providing chemical resistance suitable for use in high purity, high corrosive chemical handling applications.

Product Image-7269-07

Czynnik do chromatografii jonowymiennej, J.T. Baker®, BAKERBOND ABx™

Producent: Avantor
Opis: Prep-scale packing is intended for use at low pressure with a peristaltic pump.

MSDS Certyfikaty

Product Image-HAMI238633-1142

Elektrody pH dla przemysłu farmaceutycznego i chemicznego, EasyFerm Plus

Producent: HAMILTON BONADUZ
Opis: Elektrody EasyFerm Plus zostały zaprojektowane tak, aby wytrzymać wymagające zastosowania w przemyśle farmaceutycznym i chemicznym. Dostarczane są z elektrolitem pod ciśnieniem, który zapobiega dyfuzji próbki do czujnika.

Product Image-731-0452

Przylepne uszczelki foliowe do qPCR, QuickSeal qPCR Crystal™

Producent: iST Scientific Ltd
Opis: Clear, non-tacky, pressure sensitive film for qPCR plates (96- or 384-well) and situations where fluorescence is experienced.

Product Image-28466.292

sita molekularne (cząsteczkowe) A4, (0,4 nm, 4 Å), beads, GPR RECTAPUR® 1.6 - 2.5 mm

Producent: VWR Chemicals
Opis: VWR® 4Å Molecular Sieve is a widely used adsorbent for many different applications. It exhibits high water adsorption capacity at low partial pressures and at temperatures up to 100°C. This molecular sieve is commonly used for drying of organic liquids (solvents, oils, gasolinea and other saturated hydrocarbons, air, liquid gases (propane, butane), as well as noble and other gases (H2, N2, He, Ar, etc.).

MSDS Certyfikaty

Image Unavailable-42757.A7

żel krzemionkowy 60 0.060-0.2mm (70-230 mesh), with fluorescent indicator

Producent: Thermo Fisher Scientific
Opis: Silica gel 60 is used as carriers, processing aids, anti-caking and free-flow agents in animal feed. Defoamer applications such as paint, food, paper, textile and other industrial applications. Synthetic silicon dioxides are used as a rheology control agent in plastics. It is also used in dry column chromatography without applied pressure (gravity pulled).

MSDS Certyfikaty

Image Unavailable-MMMA7100260622

Filters, DT

Numer katalogowy: (MMMA7100260622)
Producent: 3M
Opis: For effective protection against a range of particulates, gases, and vapours, or combination hazards, use 3M™ filters DT series. Suitable for use with certain 3M™ half and full-face tight-fitting respirators in negative-pressure mode as well as 3M™ powered air respirator system PF-600E+ series.
j.m.: 1 * 10 SZT
Image Unavailable-MMMADT-1135E

Particulate Filter, DT

Numer katalogowy: (MMMADT-1135E)
Producent: 3M
Opis: For effective protection against a range of particulates, gases and vapours or combination hazards, use 3M™ filters DT-Series. Suitable for use with certain 3M™ half and full-face tight-fitting respirators in negative-pressure mode as well as 3M™ powered air respirator system PF-600E+ series.
j.m.: 1 * 10 SZT
Product Image-BRDY148666

Etykiety do drukarek laboratoryjnych BradyJet J5000

Producent: Brady
Opis: This indoor marking film is an aqueous, inkjet printable, flexible, matte finish, pressure sensitive adhesive product that is designed to be used with the BradyJet™ J5000 colour label printer.

Product Image-7024-05

J.T.Baker®, Żele krzemionkowe do chromatografii preparatywnej, niskociśnieniowe

Producent: Avantor
Opis: These are used in low pressure preparative chromatography. The mesh specifications ensure there is no excess of fines in the product which can affect flow rates and separation performance.

MSDS Certyfikaty

Image Unavailable-2879925-U

Wkładki wlotowe, FocusLiner™, Supelco®

Producent: Merck
Opis: FocusLiner™ inlet liners are designed with wool plug to promote the rapid vaporisation of the entire sample, minimise mass discrimination, and prevent non-volatile material from entering the column. It incorporates a unique design to prevent the shifting of the wool plug during repeated injections or sudden inlet pressure changes. These liners are suitable for Agilent, Perkinelmer, Shimadzu, Finnigan, Varian and Thermo scientific equipped with split/splitless inlets.

Image Unavailable-BOSSBS-0356R-CY3

Anti-NOS3 Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-0356R-CY3)
Producent: Bioss
Opis: Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-0356R-CY7

Anti-NOS3 Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-0356R-CY7)
Producent: Bioss
Opis: Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
j.m.: 1 * 100 µl
Image Unavailable-PRSI90-361

Recombinant Zmp1 M. tuberculosis (from E. coli)

Numer katalogowy: (PRSI90-361)
Producent: ProSci Inc.
Opis: M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes such as blood pressure regulation (Neprilysin or NEP1), cardiovascular development (Endothelin Converting Enzyme-1 or ECE-12), prevention of haemolytic reaction (KELL) and phosphate homeostasis (PHEX). Zmp1 is a soluble enzyme member of the M13 endopeptidases family that plays a key role in Mycobacterium tuberculosis pathogenicity with a still unknown mechanism. Recently, it was shown to suppress inflammasome activation by inhibiting caspase-1 activation, thus preventing processing of pro-IL-1beta into IL-1beta and the consequent phagosome maturation.
j.m.: 1 * 50 µG
Cena wymaga potwierdzenia u dostawcy
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
Do zakupu tego produktu może być potrzebna dodatkowa dokumentacja. Przedstawiciel VWR skontaktuje się z Tobą w razie potrzeby.
Ten produkt jest zablokowany na stronie internetowej. W celu zamówienia, skontaktuj się z Działem Obsługi Klienta.
Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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