Wyszukano: 1-Benzyl-4-cyano-4-hydroxypiperidine+hydrochloride

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Benzyl-3-cyano-4-oxopiperidine-1-carboxylate 95+%

Producent: Apollo Scientific

Opis: Benzyl-3-cyano-4-oxopiperidine-1-carboxylate 95+%

Benzyl n-cyano carbamate 95%

Numer katalogowy: (APOSOR943408-1G)

Producent: Apollo Scientific

Opis: Benzyl n-cyano carbamate 95%

j.m.: 1 * 1 g

Wyprzedaż

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2-Cyano-N-[4-(trifluoromethyl)benzyl]acetamide

Producent: Apollo Scientific

Opis: 2-Cyano-N-[4-(trifluoromethyl)benzyl]acetamide

3-Cyano-3-methylazetidine hydrochloride

Numer katalogowy: (APOSOR451025-1G)

Producent: Apollo Scientific

Opis: 3-Cyano-3-methylazetidine hydrochloride

j.m.: 1 * 1 g

Wyprzedaż

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4-Cyano-4-phenylpiperidine hydrochloride 97%

Producent: Thermo Fisher Scientific

Opis: 4-Cyano-4-phenylpiperidine hydrochloride 97%

MSDS Certyfikaty

Methyl 2-(bromomethyl)-5-cyanobenzoate 95+%

Numer katalogowy: (APOSOR15700-250MG)

Producent: Apollo Scientific

Opis: Methyl 2-(bromomethyl)-5-cyanobenzoate 95+%

j.m.: 1 * 250 mg

Wyprzedaż

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Methyl 3-(bromomethyl)-4-cyanobenzoate

Producent: Apollo Scientific

Opis: Methyl 3-(bromomethyl)-4-cyanobenzoate

Tyrphostin AG 490 ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES

Opis: AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost completely blocked the growth of all pre-B ALL cells but had no significant effect on the growth of mitogen-stimulated normal B or T cells, B-cell lymphoma or T-cell leukemia cells. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. It blocks interleukin-7-induced JAK kinase activity in T-cells (JAK-1, JAK-3) and the consequent phosphorylation of PI-3 kinase. AG-490 is cell permeable and is a valuable tool for studying the cellular role of JAK kinases in signal transduction.

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