Wyszukano: Brefeldin A

Producent: Cayman Chemical

Opis: Brefeldin A

Producent: Thermo Fisher Scientific

Opis: Brefeldin A (natural)

MSDS

Producent: Apollo Scientific

Opis: BFA is a macrolide antiobiotic. Disrupts mechanism of Golgi apparatus.

Producent: ENZO LIFE SCIENCES

Opis: GEF inhibitor

Producent: Thermo Fisher Scientific

Opis: Brefeldin A ≥99%

MSDS Certyfikaty

Producent: MP Biomedicals

Opis: Storage: Store at -20 °C.
Brefeldin A is a fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. Produced by Penicillium brefeldianum. Blocks binding of the cytosolic coat protein b-COP and ARF to Golgi membranes mediated by protein G. Also blocks protein transportation into post-Golgi compartments. It activates the sphingomyelin cycle. Brefeldin A mediated apoptosis has been observed in human tumor cells.
Brefeldin A reversibly inhibits the intracellular translocation of proteins in eukaryotes, e.g., during transport of proteins to the cell surface for secretion or expression. It has been reported to block the response of cultured cells to cholera toxin. In HepG2 cells, BFA induces two blocks in the secretory pathway; one at the level of the endoplasmic reticulum-Golgi juncture and the other in the trans-Golgi network. Brefeldin A is used in the studies of Brefeldin A-inhibited Guanine Nucleotide-exchange Protein, BIG2, Regulates the Constitutive Release of TNFR1 Exosome-like Vesicles.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.

Producent: Merck

Opis: Brefeldin A, Sigma-Aldrich®

Producent: Merck

Opis: Brefeldin A, Sigma-Aldrich®

Numer katalogowy: (SIALB5936-200UL)

Producent: Merck

Opis: Brefeldin A produced from <i>Penicillium brefeldianum</i> may be used to study protein and lipid transport between Golgi complex and the cell surface.

j.m.: 1 * 200 µl

Wyprzedaż

Numer katalogowy: (MOLEM49595136)

Producent: Molekula

Opis: Brefeldin A

j.m.: 1 * 5 mg

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