Wyszukano: ProSci Inc.

Numer katalogowy: (PRSI29-523)

Producent: ProSci Inc.

Opis: NSUN6 may have S-adenosyl-L-methionine-dependent methyl-transferase activity (Potential). NSUN6 belongs to the methyltransferase superfamily, RsmB/NOP family. It contains 1 PUA domain.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI42-063)

Producent: ProSci Inc.

Opis: Anti-MTNR1B Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI38-261)

Producent: ProSci Inc.

Opis: Anti-TNFRSF10B Rabbit Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI42-051)

Producent: ProSci Inc.

Opis: Anti-BAG6 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI38-249)

Producent: ProSci Inc.

Opis: Anti-IGFBP7 Rabbit Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI92-375)

Producent: ProSci Inc.

Opis: Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI92-367)

Producent: ProSci Inc.

Opis: PAPSS1 is a bifunctional enzyme with both ATP sulfurylase and APS kinase activity. In the N-terminal section, it belongs to the APS kinase family; while the C-terminal section belongs to the sulfate adenylyltransferase family. PAPSS1 can be inhibited by chlorate, and is expressed in many tissues, such as high endothelial venules (HEV) cells and in cartilage. PAPSS1 mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate. In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. PAPSS1 also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI92-362)

Producent: ProSci Inc.

Opis: IFN gamma is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFN gamma synthesis is induced by IL-2, FGF-basic, and EGF.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI29-540)

Producent: ProSci Inc.

Opis: FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI30-157)

Producent: ProSci Inc.

Opis: FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI42-088)

Producent: ProSci Inc.

Opis: Anti-CLEC16A Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI42-712)

Producent: ProSci Inc.

Opis: Anti-OPRK1 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI42-715)

Producent: ProSci Inc.

Opis: Anti-POLDIP2 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI30-165)

Producent: ProSci Inc.

Opis: PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI30-182)

Producent: ProSci Inc.

Opis: CEP55 plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI30-181)

Producent: ProSci Inc.

Opis: MRTO4 is a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly.This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly.

j.m.: 1 * 100 µG

Wyprzedaż