Wyszukano: ProSci Inc.

Numer katalogowy: (PRSI45-200)

Producent: ProSci Inc.

Opis: Anti-ACVRL1 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI45-201)

Producent: ProSci Inc.

Opis: Anti-ACVR1 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI91-747)

Producent: ProSci Inc.

Opis: Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI45-205)

Producent: ProSci Inc.

Opis: Anti-ADORA2 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI91-745)

Producent: ProSci Inc.

Opis: Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).

j.m.: 1 * 50 µG

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Numer katalogowy: (PRSI91-199)

Producent: ProSci Inc.

Opis: Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA and has been shown to interact with IPO13. EIF1AX contains one S1-like domain and seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

j.m.: 1 * 50 µG

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Numer katalogowy: (PRSI30-142)

Producent: ProSci Inc.

Opis: MTHFD2 is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in multiple transcripts encoding different isoforms. This gene has a pseudogene on chromosome 7.

j.m.: 1 * 100 µG

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Numer katalogowy: (PRSI30-147)

Producent: ProSci Inc.

Opis: CTH is a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in its gene cause cystathioninuria.This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI45-212)

Producent: ProSci Inc.

Opis: Anti-ADRB2 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI45-222)

Producent: ProSci Inc.

Opis: Anti-ITCH Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI45-826)

Producent: ProSci Inc.

Opis: Anti-LDHC Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI91-768)

Producent: ProSci Inc.

Opis: CD99 Antigen-Like Protein 2 (CD99L2) belongs to the CD99 family. CD99L2 is a single-pass type I membrane protein and expressed in many tissues, with low expression in thymus. CD99L2 plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI91-770)

Producent: ProSci Inc.

Opis: Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI30-823)

Producent: ProSci Inc.

Opis: ACTRT2 belongs to the actin family. Studies have shown that this protein may be involved in cytoskeletal organization similar to other cytoplasmic actin-related protein (ARP) subfamily members. Antibody raised against the human protein has been used to detect the protein by immunoblotting and immunofluorescence microscopy, demonstrating its specific synthesis in the testis, late in spermatid differentiation, and its localization in the calyx.The protein encoded by this intronless gene belongs to the actin family. Studies have shown that this protein may be involved in cytoskeletal organization similar to other cytoplasmic actin-related protein (ARP) subfamily members. Antibody raised against the human protein has been used to detect the protein by immunoblotting and immunofluorescence microscopy, demonstrating its specific synthesis in the testis, late in spermatid differentiation, and its localization in the calyx.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI30-820)

Producent: ProSci Inc.

Opis: GBP4 belongs to the GBP family. It binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. GBP4 plays a role in erythroid differentiation.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI38-231)

Producent: ProSci Inc.

Opis: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

j.m.: 1 * 500 µG

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