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Image Unavailable-BOSSBS-3051R-CY7

Anti-BAP1 Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-3051R-CY7)
Producent: Bioss
Opis: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration (PubMed:24703950). Acts as a tumor suppressor.
j.m.: 1 * 100 µl
Product Image-611-4972

Wagi precyzyjne, seria PR

Producent: OHAUS
Opis: The PR series of balances has been designed for routine weighing applications in the workplace.

Image Unavailable-BOSSBS-8411R-A350

Anti-GLIPR2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-8411R-A350)
Producent: Bioss
Opis: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
j.m.: 1 * 100 µl
Image Unavailable-PRSI33-892

Anti-PGR Mouse Monoclonal Antibody [clone: PGSR17]

Numer katalogowy: (PRSI33-892)
Producent: ProSci Inc.
Opis: Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone.
j.m.: 1 * 100 µG

New Product


Image Unavailable-USBI136879

Anti-PTPRC Mouse Monoclonal Antibody [clone: 136-4B5]

Numer katalogowy: (USBI136879)
Producent: US Biological
Opis: Anti-PTPRC Mouse Monoclonal Antibody [clone: 136-4B5]
j.m.: 1 * 400 µl
Image Unavailable-USBI151334

Anti-S100A9 Goat Polyclonal Antibody

Numer katalogowy: (USBI151334)
Producent: US Biological
Opis: Anti-S100A9 Goat Polyclonal Antibody
j.m.: 1 * 100 µG
Product Image-PRSI49-228

Anti-PRDM5 Rabbit Polyclonal Antibody

Numer katalogowy: (PRSI49-228)
Producent: ProSci Inc.
Opis: PFM2; PR domain containing 5; Official Gene Symbol- PRDM5 Gene ID- 11107(Human) Gene Map Locus- 4q25-q26(Human) PRDM5, a novel member of PR domain protein family, contains a PR-domain at the NH2 terminus followed by 16 zinc finger motifs. It is found to have a role in cell differentiation and tumorigenesis. Reports suggest PRDM5 causes G2/M arrest and apoptosis upon infection of tumor cells and has been found to be silenced in breast, ovarian and lung cancers, suggesting a potential clinical significance.
j.m.: 1 * 50 µG
Product Image-224-0033

Zestaw kompletnych pomp perystatycznych

Producent: Heidolph Instruments GmbH & Co.KG
Opis: Kompletny zestaw zawierający: napęd pompy, głowicę pompy oraz węże. Gotowy do użycia.

Image Unavailable-USBI125873

Anti-DLC-1 Rabbit Polyclonal Antibody

Numer katalogowy: (USBI125873)
Producent: US Biological
Opis: Anti-DLC-1 Rabbit Polyclonal Antibody
j.m.: 1 * 100 µl
Image Unavailable-USBI132930

Anti-S100A8 Mouse Polyclonal Antibody

Numer katalogowy: (USBI132930)
Producent: US Biological
Opis: Anti-S100A8 Mouse Polyclonal Antibody
j.m.: 1 * 50 µG
Image Unavailable-BOSSBS-3051R-A680

Anti-BAP1 Ser592 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-3051R-A680)
Producent: Bioss
Opis: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration (PubMed:24703950). Acts as a tumor suppressor.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-3051R-FITC

Anti-BAP1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numer katalogowy: (BOSSBS-3051R-FITC)
Producent: Bioss
Opis: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration (PubMed:24703950). Acts as a tumor suppressor.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-3051R-A647

Anti-BAP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-3051R-A647)
Producent: Bioss
Opis: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration (PubMed:24703950). Acts as a tumor suppressor.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-3051R-HRP

Anti-BAP1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-3051R-HRP)
Producent: Bioss
Opis: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration (PubMed:24703950). Acts as a tumor suppressor.
j.m.: 1 * 100 µl
Product Image-MILYXX8023EL0

Pompy perystaltyczne, Millipore

Numer katalogowy: (MILYXX8023EL0)
Producent: MILLIPORE
Opis: This peristaltic pump has polysulfone and steel pump head, stainless steel chassis and painted steel case.
j.m.: 1 * 1 SZT

New Product


Image Unavailable-PRSI33-189

Anti-PGR Mouse Monoclonal Antibody [clone: PR500]

Numer katalogowy: (PRSI33-189)
Producent: ProSci Inc.
Opis: This antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone.
j.m.: 1 * 100 µG

New Product


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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
Do zakupu tego produktu może być potrzebna dodatkowa dokumentacja. Przedstawiciel VWR skontaktuje się z Tobą w razie potrzeby.
Ten produkt jest zablokowany na stronie internetowej. W celu zamówienia, skontaktuj się z Działem Obsługi Klienta.
Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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