Wyszukano: LJI-308

Numer katalogowy: (BOSSBS-2739R)

Producent: Bioss

Opis: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-5545R)

Producent: Bioss

Opis: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5545R-A750)

Producent: Bioss

Opis: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-2739R-FITC)

Producent: Bioss

Opis: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5545R-FITC)

Producent: Bioss

Opis: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-11359R-A488)

Producent: Bioss

Opis: Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis and functions in an inhibitory capacity, controlling the recruitment and pooling of secretory vesicles at the plasma membrane. The Rim (Rab 3 interacting molecule) family of proteins (Rim1, Rim2, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release. Rim3, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, is a 308 amino acid member of the Rim family. Localized to the synapse and to cell junctions, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis. Rim3, a protein that may be phosphorylated upon DNA damage, is expressed throughout the body with highest levels present in brain tissue.

j.m.: 1 * 100 µl

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Numer katalogowy: (ABNOMAB10081)

Producent: Abnova

Opis: Mouse monoclonal antibody raised against TRITC.

j.m.: 1 * 200 µG

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Numer katalogowy: (BIBB701-28)

Producent: SciLabware

Opis: Screwthread tubes, Sealing rings for sliding joints, silicone rubber sheathed with PTFE, SVL® joint size 42, for tubing O.Ø 29,2 - 30,8 mm

j.m.: 1 * 10 SZT

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Numer katalogowy: (BURK0301-0500)

Producent: BURKLE

Opis: HDPE, półprzezroczysty, z zakrętką z PP.

j.m.: 1 * 1 SZT

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Numer katalogowy: (UPCHP-308)

Producent: UPCHURCH SCIENTIFIC

Opis: Upchurch Scientific®, P-308, flangeless short nuts, delrin black/ETFE yellow, 1/4-28 flat bottom port, standard knurl, for 1/8" OD tubing, 500 psi, ETFE

j.m.: 1 * 1 SZT

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Numer katalogowy: (DGINBT074)

Producent: DGP INTELSIUS

Opis: Intelsius® Biotherm packaging systems are regulatory compliant to IATA, ADR, and 49 CFR (DOT) transport regulations. These shippers utilise dry ice to maintain sample integrity during shipments from 24 to 240 hours.

j.m.: 1 * 1 SZT

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Numer katalogowy: (BROE17.160.009)

Producent: BROEN-LAB

Opis: Wall recessed eye shower with anti-corrosive cabinet.

j.m.: 1 * 1 SZT

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Numer katalogowy: (MANA732984FE)

Producent: MACHEREY-NAGEL

Opis: CHROMABOND®, CHROMABOND® Flash DL 80, PE filter elements, 30,8 mm ID

j.m.: 1 * 250 SZT

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Producent: MAPA

Opis: Te naturalne rękawice lateksowe z tekstylną wyściółką zapewniają dobry komfort podczas długotrwałej pracy w środowisku przetwarzania żywności.

Numer katalogowy: (216-0329)

Producent: Thermo Fisher Scientific

Opis: HDPE, przezierny.

j.m.: 1 * 1 SZT

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Numer katalogowy: (LAMA1138)

Producent: LAMAPLAST

Opis: Robust PP bucket with ergonomic handle. It features pressure lid with opening-off seal.

j.m.: 1 * 1 SZT

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