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Image Unavailable-BOSSBS-12873R-CY5

Anti-BMP8B Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-12873R-CY5)
Producent: Bioss
Opis: Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-6425R-A647

Anti-TRP12 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-6425R-A647)
Producent: Bioss
Opis: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-4010R-A555

Anti-ATG9A Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numer katalogowy: (BOSSBS-4010R-A555)
Producent: Bioss
Opis: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-5199R-A488

Anti-ATG9A Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-5199R-A488)
Producent: Bioss
Opis: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-1498R-CY3

Anti-FASN/Fatty Acid Synthase Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-1498R-CY3)
Producent: Bioss
Opis: Fatty acid synthetase catalyses the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-1428R-A350

Anti-Claudin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-1428R-A350)
Producent: Bioss
Opis: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11844R-A488

Anti-GEFT Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-11844R-A488)
Producent: Bioss
Opis: GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11844R-A680

Anti-GEFT Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-11844R-A680)
Producent: Bioss
Opis: GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7832R-CY5

Anti-CDC16 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-7832R-CY5)
Producent: Bioss
Opis: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-12486R-CY3

Anti-CDC16 Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-12486R-CY3)
Producent: Bioss
Opis: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-12486R-CY7

Anti-CDC16 Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-12486R-CY7)
Producent: Bioss
Opis: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-2162R-CY5

Anti-DKK1 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-2162R-CY5)
Producent: Bioss
Opis: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-2162R-CY3

Anti-DKK1 Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-2162R-CY3)
Producent: Bioss
Opis: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-4212R-CY5.5

Anti-NL1 Rabbit Polyclonal Antibody (Cy5.5®)

Numer katalogowy: (BOSSBS-4212R-CY5.5)
Producent: Bioss
Opis: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses (By similarity).
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7836R-A680

Anti-DCTN2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-7836R-A680)
Producent: Bioss
Opis: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organisation during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-1927R-CY3

Anti-PLAUR Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-1927R-CY3)
Producent: Bioss
Opis: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
j.m.: 1 * 100 µl
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
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Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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