Wyszukano: C8+ceramide

Numer katalogowy: (ENZOALX303002M025)

Producent: ENZO LIFE SCIENCES

Opis: Prepared from cerebrosides by a modified protocol of H.E. Carter et al.; J. Lipid Res. 2, 228 (1961).

j.m.: 1 * 25 mg

Wyprzedaż

Numer katalogowy: (ABCAAB85696-100)

Producent: Abcam

Opis: Anti-Ceramide synthase 1/LAG1 Goat Polyclonal Antibody

j.m.: 1 * 100 µG

Wyprzedaż

Producent: Apollo Scientific

Opis: A biologically active, cell permeable, nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10nM & activiates MAP kinase.

Numer katalogowy: (ENZOBMLSL1010005)

Producent: ENZO LIFE SCIENCES

Opis: Negative control for C2 ceramide.

j.m.: 1 * 5 mg

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-CY5.5)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-5044R-A647)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Producent: ENZO LIFE SCIENCES

Opis: Ceramide synthase inhibitor

Numer katalogowy: (BOSSBS-5044R-CY5)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-HRP)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Producent: ENZO LIFE SCIENCES

Opis: Blocks glucosylation of ceramide by inhibiting UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthetase). Inhibits the expression of cell surface glycolipid antigens and inhibits the growth of cultured rabbit skin fibroblasts. Possesses antitumor activity and inhibits Lewis lung carcinoma cell metastasis in vitro. Useful tool for studying the effects of cellular glycosphingolipid depletion. Enhances the apoptotic response to ionizing radiation by enhancing the ceramide signal.

Numer katalogowy: (BOSSBS-12976R-A680)

Producent: Bioss

Opis: Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (ENZOBMLSL1110005)

Producent: ENZO LIFE SCIENCES

Opis: Negative control for C6 ceramide.

j.m.: 1 * 5 mg

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-A680)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (ENZOBMLSL1510005)

Producent: ENZO LIFE SCIENCES

Opis: Inhibits yeast growth and activates ceramide-activated protein phosphatase (CAPP).

j.m.: 1 * 5 mg

Wyprzedaż

Numer katalogowy: (BOSSBS-12976R-A488)

Producent: Bioss

Opis: Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.

j.m.: 1 * 100 µl

Wyprzedaż

Producent: ENZO LIFE SCIENCES

Opis: A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.