Wyszukano: C2+Ceramide

Numer katalogowy: (BOSSBS-5044R-CY3)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-5044R-CY7)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-A555)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-FITC)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-12976R-A488)

Producent: Bioss

Opis: Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-A750)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Producent: ENZO LIFE SCIENCES

Opis: A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.

Numer katalogowy: (BOSSBS-12976R-CY5)

Producent: Bioss

Opis: Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-12976R-FITC)

Producent: Bioss

Opis: Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5082R-HRP)

Producent: Bioss

Opis: Lass5, or LAG1 longevity assurance homolog 5, is thought to be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donnor ceramide) in a fumonisin B1-independent manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-A350)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5044R-A488)

Producent: Bioss

Opis: Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5082R-A555)

Producent: Bioss

Opis: Lass5, or LAG1 longevity assurance homolog 5, is thought to be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donnor ceramide) in a fumonisin B1-independent manner.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-5077R-A680)

Producent: Bioss

Opis: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localised to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-12976R-A350)

Producent: Bioss

Opis: Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.

j.m.: 1 * 100 µl

Wyprzedaż