Sulindac Sulphide ≥99% (by TLC)
Dostawca: ENZO LIFE SCIENCES
Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.
- COX inhibitor
Yellow-orange solid.
Soluble in DMSO (>25mg/ml) or 100% ethanol (5mg/ml, warm).
Formuła:
C₂₀H₁₇FO₂S Temperatura przechowywania: Temperatura otoczenia |
Numer MDL:
MFCD00869764 Numer CAS: 32004-67-4 |
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