Amidepsine A ≥95% (by HPLC)
Dostawca: ENZO LIFE SCIENCES
DGAT inhibitor
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2µM) and Raji cells (IC50=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Isolated from fungal strain FO-2943.
Informacje do zamówienia: Fungal strain courtesy of the Kitasato Institute, Tokyo.
Formuła:
C₂₉H₂₉NO₁₁ |
Numer CAS:
169181-28-6 |
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