Pioglitazone ≥97% (by HPLC)
Dostawca: ENZO LIFE SCIENCES
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Uwaga
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Synonim:
5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
PPARgamma activator.
Pioglitazone selectively activates PPARγ-1. It is about one tenth as potent as rosiglitazone (EC₅₀~500 nM for human and mouse PPARγ). In a transactivation assay using COS-1 cells transfected with full length human PPARα and RXRα, pioglitazone and rosiglitazone exhibit low level activation of PPARα at 1 µM and 5.4- and 4.2-fold activation, respectively, at a concentration of 10 µM.
Soluble in DMSO (2.5 mg/ml) or dimethyl formamide (2.5 mg/ml).
Formuła:
C₁₉H₂₀N₂O₃S Temperatura przechowywania: Zamra·arka |
Numer MDL:
MFCD00865504 Numer CAS: 111025-46-8 |
Wyniki testów specyfikacyjnych
Purity | ≥97% (HPLC) |
Identity | Confirmed by ¹H-NMR |
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