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Sirtinol ≥97% (by NMR)

Dostawca: ENZO LIFE SCIENCES

Synonim: 2-(((2-Hydroxynaphthalen-1-yl)methylene)amino)-N-(1-phenylethyl)benzamide

ALX270308M001 ALX270308M005
ENZOALX270308M001EA 259 PLN
ENZOALX270308M001 ENZOALX270308M005
Sirtinol ≥97% (by NMR)
Sirtinol

SIRT inhibitor


Specific cell permeable inhibitor of the sirtuin family of NAD-dependent deacetylases (ySir2: IC50=48µM; hSIRT1: IC50=60µM; hSIRT2: IC50=58µM) with no effect on human HDAC1. Reported to inhibit Sir2p transcriptional silencing activity in vivo (IC50=25µM) and NAD-dependent histone deacetylase activity of purified recombinant yeast Sir2p (IC50=70µM) and hSIRT2 (IC50=40µM) in vitro.

Formuła: C₂₆H₂₂N₂O₂
MW: 394.46 g/mol
Numer MDL: MFCD00810186
Numer CAS: 410536-97-9

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