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Anti-GSK3B Rabbit Polyclonal Antibody

Dostawca: ENZO LIFE SCIENCES
ADIKAPST002C ADIKAPST002E
ENZOADIKAPST002CEA 990 PLN
ENZOADIKAPST002C ENZOADIKAPST002E
Anti-GSK3B Rabbit Polyclonal Antibody
Przeciwciała
Glycogen Synthase Kinase 3β (GSK-3β) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3β on serine 9, which prevents GSK-3β from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3β is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3β. The phosphorylated serineWięcej informacji o produkcie
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