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Product Image-BOSSBS-10226R

Anti-HER4 Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-10226R)
Producent: Bioss
Opis: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. Required for normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. Required for mammary gland differentiation, induction of milk proteins and lactation. Acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. Ligand specificity and signaling is modulated by alternative splicing, proteolytic processing, and by the formation of heterodimers with other ERBB family members, thereby creating multiple combinations of intracellular phosphotyrosines that trigger ligand- and context-specific cellular responses. Mediates phosphorylation of SHC1 and activation of the MAP kinases MAPK1/ERK2 and MAPK3/ERK1. Isoform JM-A CYT-1 and isoform JM-B CYT-1 phosphorylate PIK3R1, leading to the activation of phosphatidylinositol 3-kinase and AKT1 and protect cells against apoptosis. Isoform JM-A CYT-1 and isoform JM-B CYT-1 mediate reorganization of the actin cytoskeleton and promote cell migration in response to NRG1. Isoform JM-A CYT-2 and isoform JM-B CYT-2 lack the phosphotyrosine that mediates interaction with PIK3R1, and hence do not phosphorylate PIK3R1, do not protect cells against apoptosis, and do not promote reorganization of the actin cytoskeleton and cell migration.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7090R-HRP

Anti-CARD17 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-7090R-HRP)
Producent: Bioss
Opis: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-5161R-FITC

Anti-CAPZA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numer katalogowy: (BOSSBS-5161R-FITC)
Producent: Bioss
Opis: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-5161R-A647

Anti-CAPZA1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-5161R-A647)
Producent: Bioss
Opis: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
j.m.: 1 * 100 µl
Image Unavailable-USBI038240-APC

Anti-MBD4 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Numer katalogowy: (USBI038240-APC)
Producent: US Biological
Opis: Anti-MBD4 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
j.m.: 1 * 200 µl
Product Image-USBI032104-APC

Anti-ARRDC5 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Numer katalogowy: (USBI032104-APC)
Producent: US Biological
Opis: Anti-ARRDC5 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
j.m.: 1 * 200 µl
Product Image-665-0357

Wieloparametrowe sondy głębokości, MPP 930 IDS

Producent: WTW
Opis: Cyfrowe sondy głębokości z tej serii z wbudowanym czujnikiem barometrycznym i kompensacją temperatury łączą pomiary rozpuszczonego tlenu, pH lub potencjału redox oraz przewodności z dokładnym odczytem głębokości. Można je stosować z jedną, dwoma lub trzema elektrodami IDS. Do pomiarów wymagany jest miernik wieloparametrowy Multi 3430 lub Multi 3630 IDS.

Product Image-SCAA565200

Tork S5 Mini Soap and Sanitiser Dispensers

Producent: Essity
Opis: <p>Meet multiple hygiene needs with one system - wide range of soaps and sanitiser refills in foam, liquid, gel or lotion to suit the business and user's needs.</p>

New Product

Image Unavailable-BOSSBS-10433R-A680

Anti-PTGFR Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-10433R-A680)
Producent: Bioss
Opis: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate Signalling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.
j.m.: 1 * 100 µl
Product Image-MMMATR-655

Adaptery do plecaka maski filtrującej, Versaflo™

Numer katalogowy: (MMMATR-655)
Producent: 3M
Opis: The Versaflo™ Backpack Adaptor TR-655 allows users to wear Versaflo™ Powered Air Turbo TR-600 or TR-800 unit on their back when used with Versaflo™ Backpack Harness BPK-01.
j.m.: 1 * 1 SZT
Product Image-732-0003

System elektroporacji ECM® 399

Producent: BTX
Opis: The ECM 399 system is an economical electroporation system for gram negative bacteria and yeast applications. Ideal for basic transformation in research and academic labs.

Image Unavailable-BOSSBS-8481R-HRP

Anti-HLA-DMB Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-8481R-HRP)
Producent: Bioss
Opis: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
j.m.: 1 * 100 µl
Image Unavailable-MODU531213

Vitrex Safety Pen Needles with Dual Automatic Protective Shields

Producent: Vitrex Medical A/S
Opis: Vitrex safety pen needles are intended for a safe and simple insulin injection via most insulin pens. The application is the same as normal insulin pens, but they offer an automatic double protection without extra operations after using. The coloured indicator shields in the front and back-end provide a visual, physical and audible confirmation of safety. The needles are sterile and individually packed.

New Product

Image Unavailable-BOSSBS-13343R-HRP

Anti-GGA1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-13343R-HRP)
Producent: Bioss
Opis: The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
j.m.: 1 * 100 µl
Product Image-SCAA511049

Tork S1 Floor Protector for Tork Hand Sanitiser Dispenser Stand, Black

Numer katalogowy: (SCAA511049)
Producent: Essity
Opis: <p>Tork floor protector for Tork hand sanitiser dispenser stand black S1, discreet elevated design. It prevent hand sanitiser spills with this floor protector, which is designed for use with Tork hand sanitiser dispenser stands.</p>
j.m.: 1 * 1 SZT

New Product


Product Image-USBI032494-APC

Anti-BEND4 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Numer katalogowy: (USBI032494-APC)
Producent: US Biological
Opis: Anti-BEND4 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
j.m.: 1 * 200 µl
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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