Wyszukano: Tonbo Biosciences

Producent: Tonbo Biosciences

Opis: The MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion. Clone MY31 also reacts with a subset of CD14+ monocytes in non-human primates, and is reported to be cross-reactive with Chimpanzee, Cynomolgus and Rhesus.

Numer katalogowy: (25-4732-U100)

Producent: Tonbo Biosciences

Opis: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

j.m.: 1 * 100 µG

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Producent: Tonbo Biosciences

Opis: The 30-H12 antibody reacts with mouse CD90.2 (Thy1.2). CD90.2 is a strain-specific allelic form of the GPI-linked membrane associated protein CD90 and is involved in adhesion and signal transduction. CD90.2 is expressed on thymocytes, mature T cells and neurons in mouse strains that express the CD90.2 allele (BALB/c, CBA, C3H, C57BL/6, SJL and others). 30-H12 does not react with the CD90.1 allele expressed in mouse strains such as PL and AKR.

Numer katalogowy: (40-0288-U100)

Producent: Tonbo Biosciences

Opis: The CD28.6 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The CD28.6 antibody is reported to have neutralizing activity and is also useful for western blotting.

j.m.: 1 * 100 µG

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Numer katalogowy: (70-8067-M002)

Producent: Tonbo Biosciences

Opis: Goat anti-Rabbit IgG (H&L) - Affinity Pure

j.m.: 1 * 2 mg

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Numer katalogowy: (35-8076-M002)

Producent: Tonbo Biosciences

Opis: Rabbit anti-Mouse IgG (H&L) - Affinity Pure, FITC Conjugate

j.m.: 1 * 2 mg

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Numer katalogowy: (70-8037-U500)

Producent: Tonbo Biosciences

Opis: Donkey anti-Rabbit IgG (H&L), F(ab')2 Fragment- Affinity Pure, min x w/ Bovine, Chicken, Goat, Guinea Pig, Hamster, Horse, Human, Mouse, Rat or Sheep

j.m.: 1 * 0,5 mg

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Producent: Tonbo Biosciences

Opis: The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO. The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.

Numer katalogowy: (72-8094-M001)

Producent: Tonbo Biosciences

Opis: Donkey anti-Sheep IgG (H&L) - Affinity Pure, HRP Conjugate

j.m.: 1 * 1 mg

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Numer katalogowy: (72-8107-U500)

Producent: Tonbo Biosciences

Opis: Goat anti-Human Kappa (к) Light Chain - Affinity Pure, HRP Conjugate

j.m.: 1 * 0,5 mg

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Numer katalogowy: (72-8112-M001)

Producent: Tonbo Biosciences

Opis: Goat anti-Human IgG + IgA + IgM - Affinity Pure, HRP Conjugate

j.m.: 1 * 1 mg

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Numer katalogowy: (35-8081-M002)

Producent: Tonbo Biosciences

Opis: Goat anti-Chicken IgY (H&L) - Affinity Pure, FITC Conjugate

j.m.: 1 * 2 mg

Wyprzedaż

Numer katalogowy: (65-0459-T025)

Producent: Tonbo Biosciences

Opis: The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

j.m.: 1 * 25 Tests

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Producent: Tonbo Biosciences

Opis: The HIT2 antibody is specific for human CD38, a 45 kD type II transmembrane glycoprotein expressed on thymocytes, activated T and B cells, and monocytes as well as other non-hematopoietic cells. CD38 is an ectoenzyme that functions to catalyse the synthesis and hydrolysis of cyclic ADP-ribose and is involved in cell signaling, regulating cell adhesion, and activation. Additionally, CD38 has been shown to be a prognostic marker for some leukemias and other diseases

Producent: Tonbo Biosciences

Opis: The OKT8 antibody is specific for the 32 to 34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Producent: Tonbo Biosciences

Opis: The Mouse Dendritic Cell backbone panel is a six-color combination of anti-mouse antibodies. This panel can serve as a backbone for identifying major dendritic cell (DC) subsets (Duriancik DM and Hoag KA. 2009. Cytometry. 75A: 951-959). Hosts: Rat, Armenian Hamster