Wyszukano: HONEYWELL SAFETY

Numer katalogowy: (BOSSBS-7930R-A555)

Producent: Bioss

Opis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-9719R-A750)

Producent: Bioss

Opis: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterised 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialised functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-9719R-A488)

Producent: Bioss

Opis: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-9625R-CY7)

Producent: Bioss

Opis: C15orf2 may be involved in spermatogenesis. Testis-specific in adults.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-15401R-A750)

Producent: Bioss

Opis: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-7930R-HRP)

Producent: Bioss

Opis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-6231R-CY3)

Producent: Bioss

Opis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-6231R-A350)

Producent: Bioss

Opis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-13618R-CY3)

Producent: Bioss

Opis: A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-9116R-A350)

Producent: Bioss

Opis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-13594R-CY7)

Producent: Bioss

Opis: DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-8193R-A350)

Producent: Bioss

Opis: Tumor-associated antigen.Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-8193R-A555)

Producent: Bioss

Opis: Tumor-associated antigen.Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-8193R-CY7)

Producent: Bioss

Opis: Tumor-associated antigen.Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-7930R-CY5)

Producent: Bioss

Opis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-11309R-HRP)

Producent: Bioss

Opis: The testis spermatocyte apoptosis-related gene 2 protein (TSARG2, also designated spermatogenesis associated-4 or SPATA4) is involved in spermatogenesis. TSARG2 is specifically expressed in spermatogonia and spermatocytes of the seminiferous tubules, and it localizes to the nucleus. The predicted molecular weight of TSARG2 ranges depending on the species. TSARG2 is significantly upregulated in cryptorchidism and therefore, is a testis-specific apoptosis candidate oncogene.

j.m.: 1 * 100 µl

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