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Image Unavailable-SH30883.03

Wodorotlenek sodu solution 0.1 N (0.1 M), in single-use containers, HyClone™ for bioprocessing

Producent: HyClone products (Cytiva)
Opis: HyClone™ NaOH solutions in single-use bags offer a convenient format to effectively modify pH and properly care for and clean your chromatography resins.

Image Unavailable-H66517.MD

Brooker's merocyanine indicator dyed

Producent: Thermo Fisher Scientific
Opis: Brooker's merocyanine dye is used as solvent polarity indicators. It is used as pH sensors and transition metal cation indicators.

Certyfikaty

Product Image-ENTEDSU-00-01-00

Głowica dozujaca, Sentry®

Numer katalogowy: (ENTEDSU-00-01-00)
Producent: ENTEGRIS
Opis: Designed for use with FluoroPure® single-use HDPE blowmolded drums, this single-use dispense head provides dispensing functions in a single connection.
j.m.: 1 * 1 SZT
Product Image-461-0102

VWR®, Czujniki temperatury do cyrkulatorów VWR

Producent: VWR Collection
Opis: Remote temperature probes for circulator use with a chiller. Allows points of control to be switched from inside a chiller to a remote location. Compensates for heat loss through tubing between the circulator and the control point. Platinum RTD sensor with stainless steel sheath. Rubber coupling with 25,4 mm Ø, connects sheath to flexible cable. Probe cable ends in a DB9 female plug.

Image Unavailable-BOSSBS-1370R-A350

Anti-ATM Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-1370R-A350)
Producent: Bioss
Opis: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-1370R

Anti-ATM Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-1370R)
Producent: Bioss
Opis: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-1370R-HRP

Anti-ATM Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Numer katalogowy: (BOSSBS-1370R-HRP)
Producent: Bioss
Opis: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
j.m.: 1 * 100 µl
Image Unavailable-ROCKMB-110-0010

Nukleaza S1

Numer katalogowy: (ROCKMB-110-0010)
Producent: Rockland Immunochemicals
Opis: Nuclease S1 is an endonuclease that is active against single-stranded DNA and RNA molecules. Although its primary substrate is single-stranded, it can also introduce single-stranded breaks in double-stranded DNA-RNA or DNA-RNA hybrids. Nuclease S1 is used in the laboratory as a reagent in nuclease protection assays. It is used in removing single stranded tails from DNA molecules to create blunt ended molecules and opening hairpin loops generated during synthesis of double stranded cDNA.
j.m.: 1 * 10 KU
Image Unavailable-OXOIDD0011T

Krążki antybiogramowe, Krążki różnicujące (DD)

Producent: THERMO FISHER DIAGNOSTICS
Opis: Used as a screening test prior to serological grouping.

Certyfikaty

Product Image-620-1852

Sondy do rejestratorów temperatury i wilgotności

Producent: TESTO
Opis: Use the humidity/temperature probes (with an appropriate measuring instrument) for the reliable measurement of relative humidity and temperature. Humidity sensor is durable and traceable to international humidity standards, such as ILAC, PTB and NIST. Thus, even after years of use you can still count on measurement results that are reliable and correct.

Product Image-CONTTASK0850

QuickTask™ Microfibre Mop Heads

Producent: CONTEC
Opis: Single-use, 100% polyester single-loop microfibre flat mop head.

Image Unavailable-CONTMGMP0001

Jednorazowe produkty z mikrofibry, MicroGenesis

Numer katalogowy: (CONTMGMP0001)
Producent: CONTEC
Opis: These single use microfibre pads feature synthetic construction for the effective removal of both gross contamination and fine particles. Conveniently designed to provide a new pad for each new use, they are compatible with most existing hardware.
j.m.: 1 * 140 SZT
Image Unavailable-BOSSBS-6124R-A647

Anti-NBN Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-6124R-A647)
Producent: Bioss
Opis: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-6124R-HRP

Anti-NBN Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-6124R-HRP)
Producent: Bioss
Opis: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
j.m.: 1 * 100 µl
Product Image-TEST0635.9572

Sondy do testo 440

Producent: TESTO
Opis: Use the humidity/temperature probes (with an appropriate measuring instrument) for the reliable measurement of relative humidity and temperature. Humidity sensor is durable and traceable to international humidity standards, such as ILAC, PTB and NIST. Thus, even after years of use you can still count on measurement results that are reliable and correct.

Product Image-CONSSP21X

Specjalne elektrody pH

Producent: CONSORT
Opis: Electrode, pH, Single junction, refillable, pH: 0 - 14, 0...+100 °C, Szkło, Diafragma: Single junction, Elektrolit: Refillable, Ø×Dł.: 8×250 mm, S7, Do: Tall form laboratory flasks, micro volumes

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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
Do zakupu tego produktu może być potrzebna dodatkowa dokumentacja. Przedstawiciel VWR skontaktuje się z Tobą w razie potrzeby.
Ten produkt jest zablokowany na stronie internetowej. W celu zamówienia, skontaktuj się z Działem Obsługi Klienta.
Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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