Wyszukano: odf2

Numer katalogowy: (USBIB1095-06B-25)

Producent: US Biological

Opis: Anti-BID Rat Monoclonal Antibody [clone: 14F2]

j.m.: 1 * 25 µG

Wyprzedaż

Numer katalogowy: (USBI130475)

Producent: US Biological

Opis: Anti-NOS3 Mouse Monoclonal Antibody [clone: 1D12]

j.m.: 1 * 100 µG

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Numer katalogowy: (USBIC2272-88AX)

Producent: US Biological

Opis: Anti-CD22 Rat Monoclonal Antibody [clone: 5K249]

j.m.: 1 * 500 µG

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Numer katalogowy: (USBIC2272-92D)

Producent: US Biological

Opis: Anti-CD22 Mouse Monoclonal Antibody [clone: RFB4]

j.m.: 1 * 100 µG

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Numer katalogowy: (USBI124707)

Producent: US Biological

Opis: Anti-CD93 Mouse Monoclonal Antibody [clone: 3D12]

j.m.: 1 * 100 µG

Wyprzedaż

Producent: US Biological

Opis: Anti-CD72 Mouse Monoclonal Antibody [clone: 3H1667]

Producent: Abcam

Opis: Rabbit monoclonal [Y505] to CD22 (phospho Y807) - BSA and Azide free.

Numer katalogowy: (ABCAAB320445-100UL)

Producent: Abcam

Opis: APC Rabbit monoclonal [SP104] to CD22 - C-terminal.

j.m.: 1 * 100 µl

New Product Wyprzedaż

Numer katalogowy: (ABCAAB320444-100UL)

Producent: Abcam

Opis: PE Rabbit monoclonal [SP104] to CD22 - C-terminal.

j.m.: 1 * 100 µl

New Product Wyprzedaż

Numer katalogowy: (BWRLBS4018)

Producent: Bioworld Technology

Opis: Synthetic phosphopeptide derived from human ATF2 around the phosphorylation site of Threonine 71.

j.m.: 1 * 100 µG

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Numer katalogowy: (USBIC2272-98)

Producent: US Biological

Opis: Anti-CD22 Mouse Monoclonal Antibody [clone: 5B17]

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BWRLBS1022)

Producent: Bioworld Technology

Opis: Synthetic peptide, corresponding to amino acids 20-70 of Human ATF2.

j.m.: 1 * 100 µG

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Numer katalogowy: (BOSSBS-0518R-A750)

Producent: Bioss

Opis: Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro. In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-0518R-A680)

Producent: Bioss

Opis: Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro. In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type.

j.m.: 1 * 100 µl

Wyprzedaż

Producent: Biotium

Opis: Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Numer katalogowy: (BOSSBS-2985R-FITC)

Producent: Bioss

Opis: IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.

j.m.: 1 * 100 µl

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