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Numer katalogowy: (USBIA0909-42N)
Producent: US Biological
Opis: Anti-ADM2 Rabbit Polyclonal Antibody
j.m.: 1 * 200 µG


Numer katalogowy: (BOSSBS-12540R)
Producent: Bioss
Opis: ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
j.m.: 1 * 100 µl


Numer katalogowy: (USBIC2428-43-100)
Producent: US Biological
Opis: Anti-CD72 Rabbit Polyclonal Antibody
j.m.: 1 * 100 µG


Numer katalogowy: (BOSSBS-12536R)
Producent: Bioss
Opis: ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-12538R)
Producent: Bioss
Opis: ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
j.m.: 1 * 100 µl


Numer katalogowy: (USBIH0529-19)
Producent: US Biological
Opis: Anti-BDH2 Goat Polyclonal Antibody
j.m.: 1 * 100 µG


Numer katalogowy: (BOSSBS-8450R)
Producent: Bioss
Opis: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
j.m.: 1 * 100 µl


Numer katalogowy: (ABGEAP18001A)
Producent: Abgent
Opis: Anti-ADM2 Rabbit Polyclonal Antibody
j.m.: 1 * 400 µl


Numer katalogowy: (AVIVARP59862_P050)
Producent: Aviva Systems Biology
Opis: Anti-CD22 Rabbit Polyclonal Antibody
j.m.: 1 * 50 µG


Numer katalogowy: (USBIA0855-42T)
Producent: US Biological
Opis: Anti-ATF2 Rabbit Polyclonal Antibody
j.m.: 1 * 100 µG


Numer katalogowy: (USBI124777)
Producent: US Biological
Opis: Anti-CDK2 Rabbit Polyclonal Antibody
j.m.: 1 * 100 µG


Numer katalogowy: (USBI144314)
Producent: US Biological
Opis: Anti-CD22 Rabbit Polyclonal Antibody
j.m.: 1 * 100 µG


Numer katalogowy: (BOSSBS-5169R)
Producent: Bioss
Opis: ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
j.m.: 1 * 100 µl


Numer katalogowy: (USBIC2572-05N)
Producent: US Biological
Opis: Anti-CDK2 Rabbit Polyclonal Antibody
j.m.: 1 * 50 µl


Numer katalogowy: (ABCAAB281896-200)
Producent: Abcam
Opis: Anti-CD32 Mouse Monoclonal Antibody [clone: AT130-5]
j.m.: 1 * 200 µG


Numer katalogowy: (ABCAAB32355-1ML)
Producent: Abcam
Opis: Anti-CD22 (phospho Y842) Rabbit Monoclonal Antibody [clone: Y507]
j.m.: 1 * 1 mL

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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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