Wyszukano: odcz

Numer katalogowy: (BOSSBS-1341R-A750)

Producent: Bioss

Opis: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-13034R-A750)

Producent: Bioss

Opis: DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-3091R-A680)

Producent: Bioss

Opis: The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterised of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.

j.m.: 1 * 100 µl

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Producent: Biotium

Opis: Recognizes a 34 kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.

Numer katalogowy: (BOSSBS-13615R-A750)

Producent: Bioss

Opis: Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.

j.m.: 1 * 100 µl

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Producent: Abcam

Opis: Rabbit monoclonal [EPR24360-116] to MDC1 - BSA and Azide free.

Producent: Abcam

Opis: Anti-Cenexin1/ODF2 Rabbit Monoclonal Antibody [clone: EPR13561]

Numer katalogowy: (USBI033605-AP)

Producent: US Biological

Opis: Anti-CDC6 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

j.m.: 1 * 200 µl

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Numer katalogowy: (USBIC2605-54A-HRP)

Producent: US Biological

Opis: Anti-CDC6 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

j.m.: 1 * 200 µl

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Numer katalogowy: (USBI039504-AP)

Producent: US Biological

Opis: Anti-ORC2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

j.m.: 1 * 200 µl

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Numer katalogowy: (BOSSBS-2400R-A750)

Producent: Bioss

Opis: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilisation of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-13615R-A350)

Producent: Bioss

Opis: Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.

j.m.: 1 * 100 µl

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Producent: Biotium

Opis: Recognizes a 34 kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.

Numer katalogowy: (BOSSBS-5148R-A750)

Producent: Bioss

Opis: Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-13615R-FITC)

Producent: Bioss

Opis: Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BOSSBS-13615R-A680)

Producent: Bioss

Opis: Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.

j.m.: 1 * 100 µl

Wyprzedaż