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Product Image-471-0486

Lodówki laboratoryjne Liebherr, Mediline, kompaktowe

Opis: Lodówki laboratoryjne MediLine z regulatorem Comfort zapewniają maksymalną przestrzeń do przechowywania o szerokości podstawy wynoszącej 60 cm. Modele podblatowe mają wysokość 820 mm i zmieszczą się pod prawie każdym stanowiskiem laboratoryjnym. Urządzenia te spełniają wysokie wymagania chłodnictwa laboratoryjnego.
Numer katalogowy: 471-0486
j.m.: 1 * 1 SZT
Producent: Liebherr
Product Image-112-0616

Rękawice BCR™

Opis: Włókno ciągłe dziane oburęczne poliestrowe rękawice zapewniają ochronę i komfort podczas długotrwałego noszenia. Idealny pod lateksem, PCV lub innymi zewnętrznymi rękawicami, aby wchłaniać pot z rąk w czasie dłuższego noszenia.
Numer katalogowy: 112-0616
j.m.: 1 * 10 PARA
Producent: BERKSHIRE

Certyfikaty


Product Image-620-2651

VWR® Traceable®, 2 składane termometry spożywcze Second-Temp z sondą ze stali nierdzewnej

Opis: Te termometry z certyfikatem żywnościowym NSF są składane, kompaktowe i łatwe w użyciu. Składana, zabezpieczona sonda ze stali nierdzewnej umożliwia doskonałą mobilność pod dowolnym kątem w celu zmierzenia asortymentu mięs, słodyczy lub ciast. Szeroki zakres obejmuje 99 procent rutynowych kontroli temperatury.
Numer katalogowy: 620-2651
j.m.: 1 * 1 SZT
Producent: VWR Collection
Product Image-AXYGFT-384-C-R

Końcówki do robotów FLIPR Tetra, Axygen®

Opis: Te końcówki są produkowane zgodnie z rygorystycznymi specyfikacjami pod ścisłą kontrolą procesu i montowane za pomocą automatyki, aby zapewnić stałą wydajność i jakość. Zaprojektowane do stosowania w urządzeniach Molecular FLIPR Tetra.
Numer katalogowy: AXYGFT-384-C-R
j.m.: 1 * 19.200 SZT
Producent: Corning

Certyfikaty Environmentally Preferable


Product Image-444-0756

VWR® Wytrząsarka kołyskowa

Opis: Niskoprofilowa wytrząsarka kołyskowa może być używana pod większością dygestoriów i w inkubatorach. Aluminiowa podstawa zapewnia trwałość i stabilność urządzenia. Specjalnie zaprojektowane kanały znajdujące się w obudowie, zapobiegają przedostaniu się cieczy do wnętrza urządzenia. Precyzyjna kontrola prędkości zapewnia płynny ruch kołyszący do 1 min⁻¹.
Numer katalogowy: 444-0756
j.m.: 1 * 1 SZT
Producent: VWR Collection
Image Unavailable-BOSSBS-8547R

Anti-UEVLD Rabbit Polyclonal Antibody

Opis: Human papillomaviruses, particularly type 16 (designated HPV16), infect the genital tract and may lead to cervical cancer. Protection against HPV16 is thought to be provided by neutralizing directed to the major caspid protein L1 of HPV16. HPV16 L1 forms the pentameric assembly unit of the viral shell, and the binding of HPV16 L1 to the cell surface without the involvement of minor capsid protein L2 is believed to be the first step of HPV16 infection. The L1-binding domain located near the C-terminus of L2 binds L1 prior to completion of capsid assembly and is required for efficient encapsidation of the viral genome. In addition, the C-terminus of L1 is necessary for both DNA binding and DNA packaging. Expression of the late gene L1 is restricted to the upper layers of the infected epithelium. HPV16 L1 is able to package unrelated plasmid DNA in vitro and deliver the foreign DNA to eukaryotic cells with the subsequent expression of the encoded gene. L1 shows a diffuse nuclear distribution whereas L2 is localized to punctate nuclear regions identified as promonocytic leukemia protein oncogenic domains (PODs). Coexpression of L1 and L2 induces a relocalization of L1 into the PODs.
Numer katalogowy: BOSSBS-8547R
j.m.: 1 * 100 µl
Producent: Bioss
Image Unavailable-LENZ81002140

Kociołek cylinrdyczny DN ( LF ) 150, płaskie dno, średnica dna 150mm, ścianka 5mm, wyskość 290mm, na dole wylew GL 18 pod kątem 90 st. z nakrętką 1 * 1 SZT

Opis: Kociołek cylinrdyczny DN ( LF ) 150, płaskie dno, średnica dna 150mm, ścianka 5mm, wyskość 290mm, na dole wylew GL 18 pod kątem 90 st. z nakrętką 1 * 1 SZT
Numer katalogowy: LENZ81002140
j.m.: 1 * 1 SZT
Producent: Lenz Laborglas GmbH & CO.KG
Image Unavailable-BOSSBS-1975R-A647

Anti-DAXX Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Opis: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
Numer katalogowy: BOSSBS-1975R-A647
j.m.: 1 * 100 µl
Producent: Bioss
Image Unavailable-BOSSBS-1975R-HRP

Anti-DAXX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Opis: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
Numer katalogowy: BOSSBS-1975R-HRP
j.m.: 1 * 100 µl
Producent: Bioss
Image Unavailable-BOSSBS-1975R

Anti-DAXX Rabbit Polyclonal Antibody

Opis: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
Numer katalogowy: BOSSBS-1975R
j.m.: 1 * 100 µl
Producent: Bioss
Image Unavailable-BOSSBS-1975R-A680

Anti-DAXX Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Opis: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilisation. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
Numer katalogowy: BOSSBS-1975R-A680
j.m.: 1 * 100 µl
Producent: Bioss
Product Image-817-0081

Etykiety, wrażliwe na nacisk, Thermo Fisher Scientific

Opis: Te samoprzylepne etykiety poliolefinowe Nalgene™ są używane w kopiarkach, drukarkach laserowych lub drukarkach atramentowych. Akceptuje różne tusze, w tym kopiarki, markery, długopisy, żele i markery techniczne (przed użyciem należy przetestować określone tusze pod kątem przydatności), nie akceptuje ołówka.
Numer katalogowy: 817-0081
j.m.: 1 * 800 SZT
Producent: Thermo Fisher Scientific

Environmentally Preferable


Image Unavailable-BOSSBS-1975R-CY7

Anti-DAXX Rabbit Polyclonal Antibody (Cy7®)

Opis: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
Numer katalogowy: BOSSBS-1975R-CY7
j.m.: 1 * 100 µl
Producent: Bioss
Image Unavailable-BOSSBS-1975R-FITC

Anti-DAXX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Opis: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
Numer katalogowy: BOSSBS-1975R-FITC
j.m.: 1 * 100 µl
Producent: Bioss
Product Image-171-0978

Zestaw mini wkładów naukowych, arium®

Opis: Wkład dejonizacyjny arium® mini science, wykorzystujący technologię przepływu od góry do dołu, która jest zoptymalizowana pod kątem usuwania zarówno składników organicznych, jak i nieorganicznych. Zestaw został zaprojektowany aby pasował do urządzeń dostarczających wodę ultraczystą, która przekracza standard jakości ASTM Typ 1.
Numer katalogowy: 171-0978
j.m.: 1 * 1 SZT
Producent: Sartorius
Image Unavailable-BOSSBS-1975R-CY3

Anti-DAXX Rabbit Polyclonal Antibody (Cy3®)

Opis: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
Numer katalogowy: BOSSBS-1975R-CY3
j.m.: 1 * 100 µl
Producent: Bioss
609 - 624 of 94 855