Wyszukano: alpha-Cyclohexylphenylacetonitrile

Numer katalogowy: (BOSSBS-15969R-A647)

Producent: Bioss

Opis: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Zince lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30 to 40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (IMMRIR1369)

Producent: ImmunoReagents

Opis: Anti-Alpha-1-Antitrypsin Goat Polyclonal Antibody

j.m.: 1 * 1 mg

Wyprzedaż

Numer katalogowy: (ABGEAP1815A)

Producent: Abgent

Opis: Anti-AMPK alpha 1/2 Rabbit Polyclonal Antibody

j.m.: 1 * 400 µl

Wyprzedaż

Numer katalogowy: (ABCAAB285312-96)

Producent: Abcam

Opis: A sandwich ELISA kit for the quantitative measurement of TNF-alpha in biological fluids.

j.m.: 1 * 96 Tests

Wyprzedaż

Numer katalogowy: (ABCAAB39626-100)

Producent: Abcam

Opis: Rabbit polyclonal to RELM alpha/Retnla.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (ABCAAB92747-100)

Producent: Abcam

Opis: Rabbit polyclonal to GABA A Receptor alpha 6.

j.m.: 1 * 100 µG

Wyprzedaż

Producent: Thermo Fisher Scientific

Opis: α,α,α-Trifluoro-4-jodotoluen ≥98%

MSDS Certyfikaty

Producent: Thermo Fisher Scientific

Opis: α,α,α-Trifluoro-2-jodotoluen ≥99%

MSDS Certyfikaty

Producent: ENZO LIFE SCIENCES

Opis: Chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Suppresses self-renewal of embryonic stem cells.

Numer katalogowy: (M145-25G)

Producent: VWR Chemicals

Opis: An irreversible serine protease inhibitor of trypsin, chymotrypsin, kallikrein, subtilisin, and thrombin. Also inhibits the cysteine protease papain.

j.m.: 1 * 25 g

MSDS Certyfikaty Wyprzedaż

Producent: ENZO LIFE SCIENCES

Opis: Lipoxygenase inhibitor

Numer katalogowy: (BOSSBS-0486R-CY5.5)

Producent: Bioss

Opis: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (0106-100G)

Producent: VWR Chemicals

Opis: Non animal origin. White crystalline powder.

j.m.: 1 * 100 g

MSDS Certyfikaty Wyprzedaż

Producent: Abcam

Opis: Rabbit monoclonal [EPR7372] to Alpha SNAP.

Numer katalogowy: (ABCAAB51608-100)

Producent: Abcam

Opis: Rabbit monoclonal [EP1215Y] to HIF-1 alpha.

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (ABCAAB7654-250)

Producent: Abcam

Opis: Mouse monoclonal [2E3] to alpha Internexin.

j.m.: 1 * 250 µl

Wyprzedaż