Wyszukano: Tyrphostin+B7

Numer katalogowy: (PRSI92-557)

Producent: ProSci Inc.

Opis: CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20–27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumour vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumour cell migration.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI90-371)

Producent: ProSci Inc.

Opis: B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production and generation of alloreactive cytotoxic T cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumour cancer cells. The role of B7-H4 in tumour progression may be to transform precancerous cells and then protect them from immunosurveillance.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSBTEK1449)

Producent: Boster Bio

Opis: Sandwich high sensitivity ELISA kit for quantitative detection of human PD-L1/B7-H1.

j.m.: 1 * 1 KIT

Wyprzedaż

Numer katalogowy: (PRSI92-556)

Producent: ProSci Inc.

Opis: Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (PRSI54-342)

Producent: ProSci Inc.

Opis: Anti-Drd2 Rabbit Monoclonal Antibody [clone: B7]

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (ORIGCF505477)

Producent: OriGene

Opis: Anti-GADD45G Mouse Monoclonal Antibody [clone: B7]

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (PRSI90-370)

Producent: ProSci Inc.

Opis: B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting of T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production and generation of alloreactive cytotoxic T cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumour cancer cells. The role of B7-H4 in tumour progression may be to transform precancerous cells and then protect them from immunosurveillance.

j.m.: 1 * 100 µG

Wyprzedaż

Producent: Abcam

Opis: Rabbit monoclonal [EPR21841] to B7-H6.

New Product

Numer katalogowy: (ABCAAB263879-1X96)

Producent: Abcam

Opis: Mouse/Rat B7-H4 ELISA Kit

j.m.: 1 * 1 KIT

Wyprzedaż

Producent: ACROBIOSYSTEMS

Opis: Human recombinant B7-H3 (4Ig) (from HEK293)

Numer katalogowy: (PRSI90-369)

Producent: ProSci Inc.

Opis: B7H4 is a B7 family member that negatively regulates T cell immunity by inhibiting of T cell proliferation, cytokine production, and cell cycle progression. In vitro, B7H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production, and generation of alloreactive cytotoxic T-cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumour cancer cells. The role of B7-H4 in tumour progression may be to transform precancerous cells and then protect them from immunosurveillance.

j.m.: 1 * 100 µG

Wyprzedaż

Producent: Abcam

Opis: Rabbit monoclonal [EPR21841] to B7-H6 - BSA and azide free.

Numer katalogowy: (ABNOH00084901-M02)

Producent: Abnova

Opis: Anti-NFATC2IP Mouse Monoclonal Antibody [clone: 3E9-B7]

j.m.: 1 * 100 µG

Wyprzedaż

Producent: Abcam

Opis: Rabbit monoclonal [EPR28658-68] to B7-H6.

New Product

Producent: Abcam

Opis: Rabbit monoclonal [EPR23470-210] to B7-H6.

New Product

Producent: Abcam

Opis: Rabbit monoclonal [EPR26324-130] to B7-H6.

New Product