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Numer katalogowy: (BOSSBS-7905R-A750)
Producent: Bioss
Opis: Required for the polarisation of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B <i>in vitro</i> and CDC25C <i>in vitro</i> and <i>in vivo</i>.Tissue specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-9441R)
Producent: Bioss
Opis: The downstream regulatory element, DRE, acts as a location-dependent gene silencer. DREAM (for DRE-antagonist modulator) is a Ca2+-regulated transcriptional repressor that specifically binds to the DRE. DREAM regulates transcription of prodynorphin and c-Fos genes and shows 99% nucleotide homology to the Kv channel-interacting proteins (KChIPs). KChIP family members include KChIP1, which is expressed in brain, KChIP2, which is expressed in heart, brain, and lung, KChIP3 (also designated calsenilin), which is expressed in brain and testis and KChIP4.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-6480R-CY5.5)
Producent: Bioss
Opis: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-8190R-CY5)
Producent: Bioss
Opis: CSMD3 belongs to the CSMD family and contains fourteen CUB domains and twenty eight Sushi (CCP/SCR) domains. It is weakly expressed in most tissues, except in brain; expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. There are five named isoforms.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-11764R-A750)
Producent: Bioss
Opis: OPA1 is a 120 kDa protein belonging to the dynamin family. The OPA1 gene has been localised to 3q29. The gene is targeted to mitochondria and is involved in mitochondrial biogenesis. Defects in OPA1 are a cause of optic atrophy type 1. OPA1 is mostly expressed in retina but can also be expressed in brain, testis, heart and skeletal muscle.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-2345R-HRP)
Producent: Bioss
Opis: PDLIM1 is a cytoskeletal protein that may act as an adapter that brings other proteins to the cytoskeleton. PDLIM1 is strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung, and minimally expressed in liver, thymus, kidney, prostate and pancreas. It is not found in the brain, testis, ovary, and peripheral blood leukocytes.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-5720R-CY5.5)
Producent: Bioss
Opis: GDF10, or growth differentiation factor 10, bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. GDF10 is expressed in femur, brain, lung, skeletal muscle, pancreas and testis.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-7671R-CY3)
Producent: Bioss
Opis: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-7671R-CY7)
Producent: Bioss
Opis: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-5720R-FITC)
Producent: Bioss
Opis: GDF10, or growth differentiation factor 10, bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. GDF10 is expressed in femur, brain, lung, skeletal muscle, pancreas and testis.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-7683R-A555)
Producent: Bioss
Opis: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-8190R-HRP)
Producent: Bioss
Opis: CSMD3 belongs to the CSMD family and contains fourteen CUB domains and twenty eight Sushi (CCP/SCR) domains. It is weakly expressed in most tissues, except in brain; expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. There are five named isoforms.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-8190R-A680)
Producent: Bioss
Opis: CSMD3 belongs to the CSMD family and contains fourteen CUB domains and twenty eight Sushi (CCP/SCR) domains. It is weakly expressed in most tissues, except in brain; expressed at intermediate level in brain, including cerebellum, substantia nigra, thalamus, spinal cord, hippocampus and fetal brain. Also expressed in testis. There are five named isoforms.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-5767R)
Producent: Bioss
Opis: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-5767R-CY5)
Producent: Bioss
Opis: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-12286R)
Producent: Bioss
Opis: DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections.
j.m.: 1 * 100 µl


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