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Image Unavailable-90024.

5(6)-Carboxyfluorescein N-hydroxysuccinimide ester (5/6-FAM SE) ≥98% (by TLC)

Numer katalogowy: (90024.)
Producent: Biotium
Opis: 5(6)-FAM SE (full name: 5-(and-6)-Carboxyfluorescein, succinimidyl ester mixed isomers) is an amine-reactive green fluorescent dye widely used for labeling proteins or other molecules that contain a primary or secondary aliphatic amine. The coupling reaction is usually carried out at pH 8-9.5. The amide linkage from the coupling reaction is much more stable than the thiourea linkage formed from the coupling of an amine and an isothiocyanate.
j.m.: 1 * 100 mg
Image Unavailable-ENZOBMLSL2100050

D,L-threo-PDMP hydrochloride ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Blocks glucosylation of ceramide by inhibiting UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthetase). Inhibits the expression of cell surface glycolipid antigens and inhibits the growth of cultured rabbit skin fibroblasts. Possesses antitumor activity and inhibits Lewis lung carcinoma cell metastasis in vitro. Useful tool for studying the effects of cellular glycosphingolipid depletion. Enhances the apoptotic response to ionizing radiation by enhancing the ceramide signal.

Image Unavailable-ENZOBMLFA0180050

Palmitoylethanolamide ≥98% (by TLC)

Numer katalogowy: (ENZOBMLFA0180050)
Producent: ENZO LIFE SCIENCES
Opis: Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
j.m.: 1 * 50 mg
Image Unavailable-50003.

BAPTA tetrasodium salt ≥95% (by TLC) ion chelator, for calcium determination

Numer katalogowy: (50003.)
Producent: Biotium
Opis: BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.
j.m.: 1 * 1 g
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BAPTA-AM ≥98% (by TLC) ion chelator, for calcium determination

Producent: Biotium
Opis: BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

Image Unavailable-90022.

5(6)-Carboxytetramethylrhodamine succinimidyl ester [5(6)-TAMRA SE] ≥98% (by TLC) amine-reactive fluorescent dye

Numer katalogowy: (90022.)
Producent: Biotium
Opis: 5(6)-TAMRA SE (full name: 5-(and-6)-Carboxytetramethylrhodamine succinimidyl ester (mixed isomers)) is the amine reactive form of TAMRA, one of the most commonly used red fluorescent dyes. The succinimidyl ester reacts readily with primary or secondary amines under mild conditions.
j.m.: 1 * 25 mg
Image Unavailable-ENZOALX106001M025

Nω-Methyl-L-arginine monoacetate ≥99% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg).

Image Unavailable-ENZOALX105003G005

Nω-Nitro-L-arginine methyl ester hydrochloride ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Inhibitor of nitric oxide synthase (NOS). More soluble than NG-Nitro-L-arginine. Suppresses the release of nitric oxide (NO) from endothelial cells. Has a different effect on the superoxide generation by NOS than L-NMMA.

Image Unavailable-90041.

5(6)-Carboxyfluorescein diacetate NHS ester [CFSE (5(6)-CFDA SE)] ≥98% (by TLC) fluorescent pH indicator

Numer katalogowy: (90041.)
Producent: Biotium
Opis: 5(6)-CFDA, SE (full name: 5-(and-6)-Carboxyfluorescein diacetate, succinimidyl ester, also known as CFSE) is a useful fluorescent tracer that can passively diffuse into cells and covalently label intracellular proteins, resulting in long-term cell labeling.
j.m.: 1 * 25 mg

Certyfikaty


Image Unavailable-ENZOBMLEI3050010

1,9-Pyrazoloanthrone ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Potent, cell permeable, selective, and reversible inhibitor of c-Jun N-terminal kinase (JNK) (IC50=40nM for JNK-1 and JNK-2 and 90nM for JNK-3). The inhibition is competitive with respect to ATP. Exhibits over 300-fold greater selectivity for JNK as compared to ERK1 and p38. Inhibits the phosphorylation of c-Jun and blocks the expression of IL-2, IFN-γ, TNF-α, and COX-2. Blocks IL-1-induced accumulation of phospho-Jun, induction of c-Jun transcription and anti CD3-induced apoptosis of CD4+ CD8+ thymocytes.

Image Unavailable-ENZOBMLEI3910050

JZL-184 ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Potent, selective and irreversible inhibitor of MAG lipase (IC50=8nM vs 4µM for FAAH). JZL-184-treated mice displayed a number of CB1-dependent behavioral effects including analgesia, hypothermia and hypomotility as well as increased levels of 2-arachidonoylglycerol in the brain ( approx. 8-fold, with no effect on anandamide levels). JZL-184 produces a rapid and sustained blockade of brain 2-AG hydrolase activity in mice. It blocks neuropathic pain and enhances retrograde endocannabinoid signaling.

Image Unavailable-ENZOALX430049M100

Zinc protoporphyrin ≥95% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter.

Product Image-552-0240

Płytki TLC, warstwy specjalne, podłoże szklane, CHIRALPLATE

Producent: MACHEREY-NAGEL
Opis: These glass plates with a special layer are used for TLC enantiomer separations (e.g. amino acids, thiazolidine derivatives, dipeptides, lactones, α-hydroxycarboxylic acids).

Certyfikaty

Image Unavailable-ENZOBMLCA4090050

Xestospongin C ≥90% (by TLC)

Numer katalogowy: (ENZOBMLCA4090050)
Producent: ENZO LIFE SCIENCES
Opis: Xestonspongin C is a structurally novel marine alkaloid isolated from the Okinawan sponge Xestospongia sp. It is a potent, cell-permeable inhibitor of IP3 receptor-mediated Ca²⁺ release (IC50 = 358 nM). However, since xestospongin C also inhibits voltage-dependent Ca²⁺ and K⁺ currents at concentrations similar to those which inhibit the IP3 receptor, it can only be regarded as a selective blocker of the IP3 receptor in permeabilized cells and not in cells with intact plasma membranes. Has vasodilatory properties.
j.m.: 1 * 50 µG
Image Unavailable-ENZOBMLEI3270025

3'-Carbamoyl-[1,1'-biphenyl]-3-ylcyclohexylcarbamate ≥98% (by TLC)

Numer katalogowy: (ENZOBMLEI3270025)
Producent: ENZO LIFE SCIENCES
Opis: URB-597 is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), which is involved in the hydrolysis of endogenous cannabinoids such as anandamide. Inhibition of FAAH may serve to enhance the analgesic effects of endogenous cannabinoids. URB-597 has been shown to inhibit FAAH in rat cortical neuron membranes and in intact neurons with IC50 values of 4.6nM and 0.5nM, respectively. The compound has also been shown to have anxiolytic effects in rats (ID50=0.15mg/kg). Because URB-597 acts on FAAH and does not interfere with the binding of anandamide to the CB1 and CB2 receptors, it is a novel tool for drug development.
j.m.: 1 * 25 mg
Image Unavailable-USBI042865-APC

Anti-TLCD2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Numer katalogowy: (USBI042865-APC)
Producent: US Biological
Opis: Anti-TLCD2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
j.m.: 1 * 200 µl
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
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