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Image Unavailable-50007.

5,5’-Dimethyl BAPTA AM ester ≥95% (by TLC) ion chelator, for calcium determination

Numer katalogowy: (50007.)
Producent: Biotium
Opis: Dimethyl BAPTA AM ester is a membrane permeable form of Dimethyl BAPTA that can be loaded into cells by incubation. Dimethyl BAPTA AM ester itself does not bind calcium, but once inside the cell is converted into Dimethyl BAPTA by cytoplasmic esterases.
j.m.: 1 * 25 mg
Image Unavailable-ENZOBMLG2280001

α-Hydroxyfarnesylphosphonic acid (synthetic) ≥98% (by TLC)

Numer katalogowy: (ENZOBMLG2280001)
Producent: ENZO LIFE SCIENCES
Opis: Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=30 nM) and in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=35.8 µM and 67 µM respectively). α-Hydroxyfarnesylphosphonic acid inhibited (1 µM) Ras processing in Ha-ras-transformed NIH 3T3 fibroblasts.
j.m.: 1 * 1 mg
Image Unavailable-90006.

5-Carboxy-X-rhodamine triethylammonium salt single isomer ≥98% (by TLC) amine-reactive fluorescent dye

Numer katalogowy: (90006.)
Producent: Biotium
Opis: 5-ROX (full name: 5-Carboxy-X-rhodamine, triethylammonium salt, single isomer) is a single isomer, long wavelength rhodamine dye.
j.m.: 1 * 10 mg
Image Unavailable-ENZOBMLST3910005

U-73122 ≥99% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Inhibitor of PLC activation

Image Unavailable-ENZOBMLST3200100

Ono-RS-082 ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Phospholipase A2 inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose. Disrupts membrane tubule-mediated reassembly and maintenance of the Golgi complex.

Image Unavailable-ENZOBMLEI3120005

SB216763 ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.

Image Unavailable-ENZOBMLPG0500005

15-Deoxy-δ-12,14-prostaglandin J2 ≥97% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: Prostaglandin D2 derived nuclear peroxisome proliferator-activated receptor γ (PPARγ) ligand. Induces apoptosis in a number of cell types including human lung cancer cells, synoviocytes and macrophages. Promotes differentiation of fibroblasts to adipocytes. Antiinflammatory activity. Inhibits angiogenesis. Prevents TNFα induced leptin increase in mice. TRPA1 agonist. Serious doubts as to the biological relevance of this prostaglandin have been raised. Endogenous levels seem to be too low to have any effect as a PPARγ ligand.

Image Unavailable-ENZOBMLS1040025

Conduritol B epoxide ≥96% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: A potent, irreversible inhibitor of various plant β-glucosidases and mammalian glucocerebrosidase. Has been employed in in vitro and animal models for Gaucher’s disease. It raises intracellular levels of glucosylceramide by inhibiting glucosylceramidase.

Image Unavailable-ENZOBMLCA3200050

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulphonamide hydrochloride ≥98% (by TLC)

Numer katalogowy: (ENZOBMLCA3200050)
Producent: ENZO LIFE SCIENCES
Opis: Binds to calmodulin, inhibiting Ca²⁺-calmodulin-regulated enzyme activity. It inhibits the Ca²⁺/calmodulin-induced activation of myosin light chain kinase in a concentration dependent manner (IC50=25 µM). Cell permeable.
j.m.: 1 * 50 mg
Image Unavailable-50002.

BAPTA tetrapotassium salt ≥95% (by TLC) ion chelator, for calcium determination

Numer katalogowy: (50002.)
Producent: Biotium
Opis: BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium. Key advantages of these calcium chelators include relative insensitivity toward intracellular pH change and fast release of calcium.
j.m.: 1 * 1 g
Image Unavailable-ENZOBMLEI3030005

Tyrphostin AG-1296 ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: A potent inhibitor of PDGF receptor tyrosine kinase (IC50=1 µM). Also inhibits FGF receptor tyrosine kinase and c-kit. Induces apoptosis in a small-cell lung cancer cell line (H526).

Image Unavailable-ENZOBMLGR2430050

Raloxifene hydrochloride ≥98% (by TLC)

Numer katalogowy: (ENZOBMLGR2430050)
Producent: ENZO LIFE SCIENCES
Opis: A selective estrogen receptor modulator (SERM). Displays anti-estrogen action along with anti-androgen action. In clinical use for prevention of postmenopausal osteoporosis. Reduces circulating levels of IL-6 and TNFα. Inhibits prostate carcinogenesis in transgenic rat model. May be useful for the prevention of hormone-related cancers.
j.m.: 1 * 50 mg
Image Unavailable-ENZOBMLSL2300025

N-Butyldeoxynojirimycin hydrochloride ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: A novel inhibitor of glucosylceramide synthase as well as glucosidase I and II. Inhibits glucosylceramide synthase without ceramide accumulation and cell death. It is a potent inhibitor of human immunodeficiency virus (HIV) replication and syncytium formation<i> in vitro</i>. Restores chloride current in epithelial CF cells.

Image Unavailable-90033.

6-Carboxyrhodamine 6G succinimidyl ester (6-CR6G SE) ≥95% (by TLC) amine-reactive fluorescent dye

Numer katalogowy: (90033.)
Producent: Biotium
Opis: Amine-reactive form of 6-carboxyrhodamine 6G single isomer.
j.m.: 1 * 5 mg
Product Image-552-0041

Szklane kapilary i mikropipety z podziałką, jednorazowe

Producent: CAMAG
Opis: Disposable glass capillaries for manual sample application of 0,5, 1, 2, 5 or 10 µl. They can be handheld and positioned with the Multipurpose Spotting Guide (551-4230). They can also be used with Universal Capillary Holder (552-0044). Graduated 5 µl glass micropipettes are suitable for qualitative analysis on conventional TLC layers.

Image Unavailable-90029.

5-Carboxyfluorescein-N-succinimidyl ester (5-FAM SE) ≥99% (by TLC) amine-reactive fluorescent dye

Numer katalogowy: (90029.)
Producent: Biotium
Opis: 5-FAM SE is an amine-reactive form of 5-carboxyfluorescein single isomer.
j.m.: 1 * 10 mg
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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