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Image Unavailable-M1130-01

Mag-Bind® zestaw roślinnego DNA DS. 96

Producent: OMEGA BIO-TEK
Opis: The Mag-Bind® Plant DNA DS 96 Kit is designed for difficult samples (DS) which are hard to lyse or contain high amounts of polysaccharides and polyphenols. The system uses a CTAB-based lysis buffer which does not require organic solvents. The proprietary binding system prevents inhibitors from binding to the magnetic beads. The wash buffer system further removes polysaccharides, phenolic compounds and enzyme inhibitors from plant tissue lysate. An optional rebinding step is included with the kit but most samples do not require the additional treatment.

MSDS

Product Image-BSBTPB9997

Anti-CPB2 Rabbit Polyclonal Antibody

Numer katalogowy: (BSBTPB9997)
Producent: Boster Bio
Opis: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
j.m.: 1 * 100 µG
Product Image-BSBTPB9998

Anti-CPB2 Rabbit Polyclonal Antibody

Numer katalogowy: (BSBTPB9998)
Producent: Boster Bio
Opis: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
j.m.: 1 * 100 µG
Image Unavailable-SPCMD1033-500MLGL

Diethanolamine ≥98.5% ACS

Numer katalogowy: (SPCMD1033-500MLGL)
Producent: Spectrum Chemical
Opis: Diethanolamine, Reagent, ACS is also referred to as DEA, is an organic compound that in its pure form is a white solid but it is most often encountered as a clear liquid that has a viscous texture. It is a secondary amine and diol and is water soluble. It is used as a corrosion inhibitor and surfactant that is used in the oil refining industry to help remove hydrogen sulfide from sour gas. As an ACS grade reagent, Spectrum Chemical manufactured compound is used as the quality standard against which other substances are grade and has met the toughest regulatory standards for quality and pureness
j.m.: 1 * 500 mL
Product Image-PRSI3863

Anti-UNG1 Rabbit Polyclonal Antibody

Numer katalogowy: (PRSI3863)
Producent: ProSci Inc.
Opis: UNG1 Antibody: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing. While UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from nuclear DNA that arise through either misincorporation during replication or cytosine deamination, inhibition of UNG1 by uracil glycosylase inhibitor did not lead to increased levels of spontaneous or induced mitochondrial DNA mutations. However, decreased levels of UNG activity and increased oxidative damage to mitochondrial DNA were seen in older mice, suggesting that mitochondrial DNA repair mechanisms may be involved in various neurodegenerative disorders in an age-dependent manner. This UNG1 antibody will not cross-react with UNG2.
j.m.: 1 * 100 µG
Product Image-PRSI3865

Anti-UNG1 Rabbit Polyclonal Antibody

Numer katalogowy: (PRSI3865)
Producent: ProSci Inc.
Opis: UNG1 Antibody: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing. While UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from nuclear DNA that arise through either misincorporation during replication or cytosine deamination, inhibition of UNG1 by uracil glycosylase inhibitor did not lead to increased levels of spontaneous or induced mitochondrial DNA mutations. However, decreased levels of UNG activity and increased oxidative damage to mitochondrial DNA were seen in older mice, suggesting that mitochondrial DNA repair mechanisms may be involved in various neurodegenerative disorders in an age-dependent manner. This UNG1 antibody will not cross-react with UNG2.
j.m.: 1 * 100 µG
Product Image-PRSI79-244

Anti-HDAC4/5/9 Rabbit Polyclonal Antibody

Numer katalogowy: (PRSI79-244)
Producent: ProSci Inc.
Opis: Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups from lysine residues in histones and non-histone proteins, resulting in transcriptional repression. In general, they do not act autonomously but as components of large multiprotein complexes, such as pRb-E2F and mSin3A, that mediate important transcription regulatory pathways. There are three classes of HDACs; classes 1, 2 and 4, which are closely related Zn2+-dependent enzymes. HDACs are ubiquitously expressed and they can exist in the nucleus or cytosol. Their subcellular localization is effected by protein-protein interactions (for example HDAC-14.3.3 complexes are retained in the cytosol) and by the class to which they belong (class 1 HDACs are predominantly nuclear whilst class 2 HDACs shuttle between the nucleus and cytosol). HDACs have a role in cell growth arrest, differentiation and death and this has led to substantial interest in HDAC inhibitors as possible antineoplastic agents.
j.m.: 1 * 100 µG
Product Image-PRSI3023

Anti-BCL2L13 Rabbit Polyclonal Antibody

Numer katalogowy: (PRSI3023)
Producent: ProSci Inc.
Opis: Bcl-rambo Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A novel, widely expressed member termed Bcl-rambo was recently identified. This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2. Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs, but unlike Bcl-2, the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion. This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions, suggesting that Bcl-rambo may be important other pro-apoptotic pathways.
j.m.: 1 * 100 µG
Image Unavailable-ICNA0219471401

nikotynamid adeniny, dinukleotyd (forma utleniona) ≥98%, white powder cell culture reagent

Producent: MP Biomedicals
Opis: Storage: -20°C, desiccate
This is an ultrapure NAD, chromatographically purified to remove trace inhibitors.
β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain.
Many metabolites and enzymes of biological interest are present in tissues at low concentrations. With the use of β-NAD as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling, much greater sensitivity for detection of these components is achieved. The reduced form, β-NADH, is fluorescent whereas β-NAD is not. This difference in fluorescence provides a sensitive fluorescent measurement of the oxidized or reduced pyridine nucleotides at concentrations down to 10-7 M.
Electron acceptor. β-NAD is a carrier for hydride ion, forming b-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to b-NAD to form the reduced product, b-NADH. Unlike b-NAD which has no absorbance at 340 nm, b-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of b-NADH is the basis for measurement of activity of many enzymes.

Image Unavailable-116556050.

SPINeasy® RNA Kit for Feces

Numer katalogowy: (116556050.)
Producent: MP Biomedicals
Opis: <p>The SPINeasy® RNA Kit for Feces delivers high yields of pure RNA without detectable DNA contamination in less than 20 min, making it particularly suitable for downstream applications, such as qPCR and RT-qPCR without the need of further inhibitor/DNA removal steps.</p>
j.m.: 1 * 50 Tests

New Product


Product Image-R6874-02

Zestaw RNA wirusowego E.Z.N.A.®

Producent: OMEGA BIO-TEK
Opis: The E.Z.N.A.® Viral RNA Kit is designed for the isolation of viral RNA from cell free fluids such as plasma, serum, urine and cell culture supernatant. The procedure completely removes contaminants and enzyme inhibitors making viral RNA isolation fast, convenient and reliable. The kit is also suitable for the isolation of total RNA from cultured cells, tissues and bacteria. RNA purified using the E.Z.N.A.® Viral RNA method is ready for all downstream applications such as RT-PCR.

MSDS Certyfikaty

Product Image-27362.296

AMBERLITE ® IRN-77, żywica jonowymienna kationowa typ (H+)

Numer katalogowy: (27362.296)
Producent: VWR Chemicals
Opis: DuPont™ AmberLite™ IRN77 H Ion Exchange Resin Nuclear-grade, Uniform Particle Size, Gel, Strong Acid Cation Exchange Resin for Water Treatment Applications in the Nuclear Power Industry.
j.m.: 1 * 1 kg

MSDS Certyfikaty


Product Image-4631-01

Ion exchange resins, beads, BAKER ANALYZED® IONAC® Postać NM-60 H+/OHˉ, Typ I oczko 16–50 (mixed bed exchanger), J.T.Baker®

Numer katalogowy: (4631-01)
Producent: Avantor
Opis: Ion exchange resins, beads, BAKER ANALYZED® IONAC® Postać NM-60 H+/OHˉ, Typ I oczko 16–50 (mixed bed exchanger), J.T.Baker®
j.m.: 1 * 500 g

MSDS Certyfikaty


Product Image-786-311

Żywice oczyszczania metodą powinowactwa, Glutathione Resin

Producent: G-Biosciences
Opis: Glutathione resin is designed for the affinity purification of proteins with a glutathione S-transferase (GST) tag. The resin consists of reduced glutathione (GSH) covalently coupled to 4% cross-linked agarose, via a 10-carbon spacer arm. The resin has a binding capacity of ~8 mg GST/ml resin. Supplied as slurry in 20% ethanol.

Image Unavailable-R6814-00

Zestaw RNA krwi E.Z.N.A.®

Producent: OMEGA BIO-TEK
Opis: The E.Z.N.A.® Blood RNA Kit is designed for the isolation of total intracellular RNA from up to 1 ml of fresh, or frozen whole blood treated with any common anticoagulant such as heparin, EDTA or acid-citrate-dextrose. The procedure completely removes contaminants and enzyme inhibitors making total RNA isolation fast, convenient and reliable. Red blood cells are selectively lysed and white cells are collected by centrifugation. After lysis of white blood cells under denaturing conditions that inactivate RNases, the lysate is homogenised with a homogeniser spin column. The sample is then applied to a HiBind® spin column. Cellular debris and other contaminants such as haemoglobin are effectively washed away and high-quality RNA is finally eluted in DEPC treated water.

MSDS Certyfikaty

Product Image-7899-05

J.T.Baker® BAKERBOND® PROchievA™, Affinity Chromatography Resin, Recombinant Protein A

Producent: Avantor
Opis: The J.T.Baker<sup>®</sup> BAKERBOND<sup>®</sup> PROchievA™ protein A resin offers superior dynamic binding capacity with excellent alkaline stability linked to Avantor's proprietary ligand.

MSDS Certyfikaty

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