Wyszukano: DWK Life Sciences

Opis: Methotrexate

Numer katalogowy: ENZOALX440045M050

j.m.: 1 * 50 mg

Producent: ENZO LIFE SCIENCES

Wyprzedaż

Opis: An antineoplastic agent which acts as an antimetaboliteof folic acid.

Numer katalogowy: APOSBIM0130-1G

j.m.: 1 * 1 g

Producent: Apollo Scientific

Wyprzedaż

Opis: Methotrexate

Numer katalogowy: PROOMM0040.00

j.m.: 1 * 500 mg

Producent: LGC Standards PROMOCHEM

Wyprzedaż

Opis: Methotrexate

Numer katalogowy: PROOICRS0345

j.m.: 1 * 100 mg

Producent: LGC Standards PROMOCHEM

Wyprzedaż

Opis: Methotrexate hydrate 99%

Numer katalogowy: ACRO208100250

j.m.: 1 * 25 mg

Producent: Thermo Fisher Scientific

MSDS Wyprzedaż

Opis: Methotrexate

Numer katalogowy: J63075.MC

j.m.: 1 * 100 mg

Producent: Thermo Fisher Scientific

MSDS Certyfikaty Wyprzedaż

Opis: Methotrexate, Sigma-Aldrich®

Numer katalogowy: SIALM9929-100MG

j.m.: 1 * 100 mg

Producent: Merck

Wyprzedaż

Opis: Methotrexate hydrate

Numer katalogowy: MOLEM80419974

j.m.: 1 * 100 mg

Producent: Molekula

Wyprzedaż

Opis: Folic Acid antagonist; structurally similar to folic acid. Methotrexate is a mixture of 4-amino-10-methylfolic acid and closely related compounds.

Numer katalogowy: ICNA0210229910

j.m.: 1 * 10 mg

Producent: MP Biomedicals

Wyprzedaż

Opis: Sodium methotrexate 98.5%

Numer katalogowy: J66364.MD

j.m.: 1 * 250 mg

Producent: Thermo Fisher Scientific

Certyfikaty Wyprzedaż

Opis: Methotrexate hydrate, Sigma-Aldrich®

Numer katalogowy: SIALM8407-500MG

j.m.: 1 * 500 mg

Producent: Merck

Wyprzedaż

Opis: Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.

Numer katalogowy: ICNA0219985580

j.m.: 1 * 100 mg

Producent: MP Biomedicals

Wyprzedaż

Opis: Methotrexate hydrate, Sigma-Aldrich®

Numer katalogowy: SIAL06563-25MG

j.m.: 1 * 25 mg

Producent: Merck

Wyprzedaż

Opis: Fluorescein methotrexate is useful for studying anti-metabolite resistance and spontaneous gene amplification. The dye is actively taken up by cells and binds to dihydrofolate reductase (DHFR) quantitatively.

Numer katalogowy: 00023.

j.m.: 1 * 1 mg

Producent: Biotium

Wyprzedaż

Opis: Anti-Methotrexate Goat Polyclonal Antibody

Numer katalogowy: USBIM3101-01A

j.m.: 1 * 100 µl

Producent: US Biological

Wyprzedaż

Opis: Anti-Methotrexate Sheep Polyclonal Antibody

Numer katalogowy: USBIM3101-01D

j.m.: 1 * 500 µl

Producent: US Biological

Wyprzedaż