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Image Unavailable-ENZOENZCHM1230005

MMP-13 inhibitor ≥99% (by HPLC)

Producent: ENZO LIFE SCIENCES
Opis: Potent MMP-13 inhibitor.

New Product

Image Unavailable-ENZOBMLEI3020005

CL-82198 (MMP-13 inhibitor) ≥98% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: A novel and selective inhibitor of MMP-13 (89% at 33 µM). Acts via binding to the S1' pocket of MMP-13 without metal chelation.

New Product

Image Unavailable-ENZOBMLAK4120001

Zestaw tesowy do detekcji metodą kolorymetryczną metaloproteinazy macierzy-13 (MMP-13)

Numer katalogowy: (ENZOBMLAK4120001)
Producent: ENZO LIFE SCIENCES
Opis: A QuantiZyme™ Assay System. The MMP-13 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a thiopeptide as a chromogenic substrate.
j.m.: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK4130001

Zestaw tesowy do detekcji metodą fluorometryczną metaloproteinazy macierzy-13 (MMP-13)

Numer katalogowy: (ENZOBMLAK4130001)
Producent: ENZO LIFE SCIENCES
Opis: A QuantiZyme™ Assay System. The MMP-13 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.
j.m.: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLP2350001

ADAM Substrate

Numer katalogowy: (ENZOBMLP2350001)
Producent: ENZO LIFE SCIENCES
Opis: Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.
j.m.: 1 * 1 mg

New Product


Image Unavailable-ENZOBMLP1450001

Cathepsin D & E substrate (fluorogenic)

Numer katalogowy: (ENZOBMLP1450001)
Producent: ENZO LIFE SCIENCES
Opis: Quenched fluorogenic substrate for cathepsin D (kcat/Km=1,09×10 M-1s-1) and cathepsin E (kcat/Km=1,56×10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.
j.m.: 1 * 1 mg

New Product


Product Image-ENZOBMLP1320500

TACE substrate (fluorogenic)

Numer katalogowy: (ENZOBMLP1320500)
Producent: ENZO LIFE SCIENCES
Opis: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).
j.m.: 1 * 0,5 mg

New Product


Image Unavailable-PRSI91-415

Human recombinant TIMP2 (from cells)

Numer katalogowy: (PRSI91-415)
Producent: ProSci Inc.
Opis: Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
j.m.: 1 * 50 µG
Image Unavailable-PRSI91-412

Human recombinant TIMP1 (from cells)

Numer katalogowy: (PRSI91-412)
Producent: ProSci Inc.
Opis: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
j.m.: 1 * 50 µG
Image Unavailable-PRSI92-603

Mouse recombinant TIMP1

Numer katalogowy: (PRSI92-603)
Producent: ProSci Inc.
Opis: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
j.m.: 1 * 50 µG
Image Unavailable-ENZOENZCHM1330001

MMP-​9 inhibitor I ≥97% (by HPLC)

Numer katalogowy: (ENZOENZCHM1330001)
Producent: ENZO LIFE SCIENCES
Opis: Cell-permeable, potent, selective, and reversible MMP-9 inhibitor.
j.m.: 1 * 1 mg

New Product


Image Unavailable-ENZOALX260165M005

MMP-3 inhibitor ≥95% (by HPLC)

Numer katalogowy: (ENZOALX260165M005)
Producent: ENZO LIFE SCIENCES
Opis: Inhibitor of matrix metalloproteinase 3 (MMP-3) (IC50=5µM).
j.m.: 1 * 5 mg

New Product


Image Unavailable-ENZOBMLAK3080001

Zestaw do profilowania inhibitorów MMP

Numer katalogowy: (ENZOBMLAK3080001)
Producent: ENZO LIFE SCIENCES
Opis: The MMP inhibitor profiling kit, fluorometric RED is a complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes, using a quenched fluorogenic substrate OMNIMMP® RED.
j.m.: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK0160001

Zestaw do profilowania inhibitorów MMP, fluorometryczny

Numer katalogowy: (ENZOBMLAK0160001)
Producent: ENZO LIFE SCIENCES
Opis: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a sensitive fluorogenic substrate . Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
j.m.: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLAK0150001

Zestaw do profilowania inhibitorów MMP, kolorymetryczny

Numer katalogowy: (ENZOBMLAK0150001)
Producent: ENZO LIFE SCIENCES
Opis: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a chromogenic substrate1,2 detected at 412 nm. Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
j.m.: 1 * 1 KIT

New Product


Image Unavailable-ENZOBMLPI1150005

NNGH ≥99% (by TLC)

Producent: ENZO LIFE SCIENCES
Opis: MMP inhibitor

New Product

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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
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