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Image Unavailable-BOSSBS-11243R-CY3

Anti-RAB17 Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-11243R-CY3)
Producent: Bioss
Opis: Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-2960R-A488

Anti-KCNJ1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-2960R-A488)
Producent: Bioss
Opis: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-2960R-HRP

Anti-KCNJ1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-2960R-HRP)
Producent: Bioss
Opis: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11334R-A647

Anti-APBA1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-11334R-A647)
Producent: Bioss
Opis: The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the ∫-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11å (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11334R-A350

Anti-APBA1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-11334R-A350)
Producent: Bioss
Opis: The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the ∫-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11å (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-8601R-CY5

Anti-SLC9A3 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-8601R-CY5)
Producent: Bioss
Opis: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-8601R

Anti-SLC9A3 Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-8601R)
Producent: Bioss
Opis: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
j.m.: 1 * 100 µl
Product Image-THSARVT450-230

Savant™ SpeedVac™ RVT450 Refrigerated Vapour Trap

Numer katalogowy: (THSARVT450-230)
Producent: THERMO SAVANT
Opis: RVT450-230 is a robust and efficient rotary vane vacuum pump designed for a wide range of industrial applications. It offers a high pumping speed and ultimate vacuum performance, ensuring reliable and consistent operation. The pump features a durable construction with advanced materials, providing long-lasting service life and minimal maintenance requirements. It operates on a 230 V power supply, making it suitable for various international settings. Ideal for use in laboratories, manufacturing processes, and other demanding environments, the RVT450-230 is a versatile and dependable choice for your vacuum needs.
j.m.: 1 * 1 SZT
Product Image-PRSI56-874

Anti-CD320 Rabbit Polyclonal Antibody

Numer katalogowy: (PRSI56-874)
Producent: ProSci Inc.
Opis: The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).
j.m.: 1 * 400 µl
Image Unavailable-PRSI33-046

Anti-C5ar2 Rabbit Polyclonal Antibody

Numer katalogowy: (PRSI33-046)
Producent: ProSci Inc.
Opis: G protein receptors, also called GPRs, GPCRs, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members. These receptors sense stimuli outside, convey the signal across the cell membrane, and activate internal signal transduction pathways and cellular responses. GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, and possibly act as a decoy receptor. It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity.
j.m.: 1 * 100 µG
Image Unavailable-BOSSBS-2960R-CY5.5

Anti-KCNJ1 Rabbit Polyclonal Antibody (Cy5.5®)

Numer katalogowy: (BOSSBS-2960R-CY5.5)
Producent: Bioss
Opis: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-5372R-CY5.5

Anti-GIT1 Rabbit Polyclonal Antibody (Cy5.5®)

Numer katalogowy: (BOSSBS-5372R-CY5.5)
Producent: Bioss
Opis: Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-5373R-A488

Anti-GIT1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-5373R-A488)
Producent: Bioss
Opis: Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11334R

Anti-APBA1 Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-11334R)
Producent: Bioss
Opis: The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the ∫-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11å (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-12176R

Anti-KCNJ1 Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-12176R)
Producent: Bioss
Opis: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11334R-CY5

Anti-APBA1 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-11334R-CY5)
Producent: Bioss
Opis: The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the ∫-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11å (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).
j.m.: 1 * 100 µl
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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