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Image Unavailable-BOSSBS-1817R-A750

Anti-Pro-NRG1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numer katalogowy: (BOSSBS-1817R-A750)
Producent: Bioss
Opis: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
j.m.: 1 * 100 µl
Product Image-USBIF4523-01B

Anti-FOXO1 Rabbit polyclonal antibody

Numer katalogowy: (USBIF4523-01B)
Producent: US Biological
Opis: Anti-FOXO1 Rabbit polyclonal antibody
j.m.: 1 * 200 µl
Image Unavailable-BOSSBS-7090R-A750

Anti-CARD17 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numer katalogowy: (BOSSBS-7090R-A750)
Producent: Bioss
Opis: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7090R-A555

Anti-CARD17 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numer katalogowy: (BOSSBS-7090R-A555)
Producent: Bioss
Opis: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-10306R-A555

Anti-TREM1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numer katalogowy: (BOSSBS-10306R-A555)
Producent: Bioss
Opis: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-10306R-A647

Anti-TREM1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-10306R-A647)
Producent: Bioss
Opis: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-10306R-A680

Anti-TREM1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-10306R-A680)
Producent: Bioss
Opis: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
j.m.: 1 * 100 µl
Image Unavailable-PRSI91-089

Human Recombinant BID (from E. coli)

Numer katalogowy: (PRSI91-089)
Producent: ProSci Inc.
Opis: BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.
j.m.: 1 * 0,05 mg

New Product


Product Image-ABCAAB184787-100

Anti-Caspase-3 Rabbit Monoclonal Antibody [clone: EPR18297]

Numer katalogowy: (ABCAAB184787-100)
Producent: Abcam
Opis: Rabbit monoclonal [EPR18297] to Caspase-3.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-1346R-A555

Anti-TRP73 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numer katalogowy: (BOSSBS-1346R-A555)
Producent: Bioss
Opis: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-10306R-HRP

Anti-TREM1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-10306R-HRP)
Producent: Bioss
Opis: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-13671R-A680

Anti-TAX1BP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-13671R-A680)
Producent: Bioss
Opis: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-13671R-CY7

Anti-TRAF6BP Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-13671R-CY7)
Producent: Bioss
Opis: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7090R-CY5

Anti-CARD17 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-7090R-CY5)
Producent: Bioss
Opis: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7090R-CY7

Anti-CARD17 Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-7090R-CY7)
Producent: Bioss
Opis: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
j.m.: 1 * 100 µl
Image Unavailable-ENZOADISPP8921

Recombinant thioredoxin (from E. coli), HIS tag

Numer katalogowy: (ENZOADISPP8921)
Producent: ENZO LIFE SCIENCES
Opis: Thioredoxin (Trx) is a redox protein of approximately 12 kDa. Its primary domain is conserved across a number of Trx family members and contains a conserved catalytic site Cys-Gly-Pro-Cys. It is ubiquitous and found in many organisms from bacteria to mammals. Trx has been shown to function in cell proliferation, redox signaling and inhibition of apoptosis.
j.m.: 1 * 1 mg
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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