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Image Unavailable-BOSSBS-5474R-CY7

Anti-MBP Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-5474R-CY7)
Producent: Bioss
Opis: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-4216R-A647

Anti-SGMS1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-4216R-A647)
Producent: Bioss
Opis: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-4216R-A488

Anti-SGMS1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-4216R-A488)
Producent: Bioss
Opis: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-4947R

Anti-IL1A Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-4947R)
Producent: Bioss
Opis: Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin 1 alpha (IL1 alpha) and interleukin 1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-6763R-A488

Anti-MSR1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-6763R-A488)
Producent: Bioss
Opis: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-5721R

Anti-MBNL3 Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-5721R)
Producent: Bioss
Opis: MBNL3 has been shown to inhibit muscle differentiation. MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators. This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, neurons, adipocytes and blood cell types. MBNL3 is expressed in myoblasts, muscle precursor cells, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes. MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7546R-CY5

Anti-BCAM Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-7546R-CY5)
Producent: Bioss
Opis: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-8317R-CY5.5

Anti-HDHD2 Rabbit Polyclonal Antibody (Cy5.5®)

Numer katalogowy: (BOSSBS-8317R-CY5.5)
Producent: Bioss
Opis: HDHD2 (haloacid dehalogenase-like hydrolase domain containing 2) is also known as DKFZp564D1378 and is a 259 amino acid protein that is expressed as two isoforms produced by alternative splicing. HDHD2 belongs to the HAD-like hydrolase superfamily, which contains a group of hydrolase enzymes that differ from the å/∫
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-8317R-A647

Anti-HDHD2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-8317R-A647)
Producent: Bioss
Opis: HDHD2 (haloacid dehalogenase-like hydrolase domain containing 2) is also known as DKFZp564D1378 and is a 259 amino acid protein that is expressed as two isoforms produced by alternative splicing. HDHD2 belongs to the HAD-like hydrolase superfamily, which contains a group of hydrolase enzymes that differ from the å/∫
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-8317R-CY5

Anti-HDHD2 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-8317R-CY5)
Producent: Bioss
Opis: HDHD2 (haloacid dehalogenase-like hydrolase domain containing 2) is also known as DKFZp564D1378 and is a 259 amino acid protein that is expressed as two isoforms produced by alternative splicing. HDHD2 belongs to the HAD-like hydrolase superfamily, which contains a group of hydrolase enzymes that differ from the å/∫
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7069R-CY5.5

Anti-GADD45G Rabbit Polyclonal Antibody (Cy5.5®)

Numer katalogowy: (BOSSBS-7069R-CY5.5)
Producent: Bioss
Opis: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
j.m.: 1 * 100 µl
Product Image-USBI036639

Anti-HMGB3 Rabbit Polyclonal Antibody

Numer katalogowy: (USBI036639)
Producent: US Biological
Opis: Anti-HMGB3 Rabbit Polyclonal Antibody
j.m.: 1 * 200 µl
Image Unavailable-BC91

Sulphosuccinimidyl acetate (Sulpho-NHS-acetate)

Numer katalogowy: (BC91)
Producent: G-Biosciences
Opis: Sulpho NHS acetate is a small, water-soluble compound used for blocking primary amines by acylation. It covalent bonds with amine groups to prevent specific interactions and conjugations. It is water-soluble and reacts at pH 7 to 9.
j.m.: 1 * 100 mg

Certyfikaty


Image Unavailable-BOSSBS-9561R-A350

Anti-LACTB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-9561R-A350)
Producent: Bioss
Opis: Penicillin refers to any member of beta-lactam antibiotics group. These agents are identified by a beta-lactam ring within their molecular structure. As the most widely used group of antibiotics available, beta-lactams are used for the treatment of bacterial infections usually caused by gram-positive organisms. Beta-lactam antibiotics are bactericidal, functioning to inhibit the synthesis of the peptidoglycan layer of bacterial cell walls. Bacterial penicillin-binding proteins and beta-lactamases constitute a large family of serine proteases that perform essential functions in the synthesis and maintenance of peptidoglycan cell wall. Notably, beta-lactamases cleave beta-lactams, therefore providing the bacteria with resistance to the antibiotic. Homologues of beta-lactamases occur in many species, including human, rat, cow, rabbit, pig, xenopus, zebrafish, and C. elegans. The human homologues, LACTB and LACTB2, are active-site-serine enzymes thought to be involved in metabolism.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-2352R-A555

Anti-CYP2B6 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numer katalogowy: (BOSSBS-2352R-A555)
Producent: Bioss
Opis: Cytochromes P45 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase.
j.m.: 1 * 100 µl
Image Unavailable-ENZOADI905710100

Anti-TLR2 Rabbit Polyclonal Antibody

Numer katalogowy: (ENZOADI905710100)
Producent: ENZO LIFE SCIENCES
Opis: The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands.
j.m.: 1 * 100 µG
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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