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Numer katalogowy: (BSENS-075-50)
Producent: Biosensis
Opis: Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. Alpha synuclein has been associated with several neurodegenerative diseases. A point mutation in the gene coding for the alpha-synuclein protein was the first discovery linking this protein to a rare familial form of Parkinson's disease (PD). Subsequently, other mutations in the alpha-synuclein gene have been identified in familial PD. The aggregated proteinaceous inclusions called Lewy bodies found in PD and cortical Lewy body dementia (LBD) were discovered to be predominantly alpha-synuclein. Aberrant aggregation of alpha-synuclein has been detected in an increasing number of neurodegenerative diseases, collectively known as synucleopathies. Alpha-synuclein exists physiologically in both soluble and membrane-bound states, in unstructured and alpha-helical conformations, respectively. The physiological function of alpha-synuclein appears to require its translocation between these subcellular compartments and interconversion between the 2 conformations. Abnormal processing of alpha-synuclein is predicted to lead to pathological changes in its binding properties and function.
j.m.: 1 * 50 µG


Numer katalogowy: (PRSI26-102)
Producent: ProSci Inc.
Opis: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
j.m.: 1 * 50 µG


Numer katalogowy: (BSNC59003)
Producent: Basan
Opis: [EN]PUSH-PULL HOE 270 MM BLUE 1 * 1 SZT
j.m.: 1 * 1 SZT


Numer katalogowy: (AESCDB345R)
Producent: Aesculap
Opis: [EN]HOE,GOLDMANN-FOX,(GF5),GREEN 1 * 1 SZT
j.m.: 1 * 1 SZT


Numer katalogowy: (PRSI40-619)
Producent: ProSci Inc.
Opis: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues. Recombinant rat IL-4 is a 14.0 kDa globular protein containing 126 amino acid residues. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues.
j.m.: 1 * 20 µG


Numer katalogowy: (PRSI40-604)
Producent: ProSci Inc.
Opis: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues. Recombinant rat IL-4 is a 14.0 kDa globular protein containing 126 amino acid residues. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues.
j.m.: 1 * 20 µG


Numer katalogowy: (BSNC59006)
Producent: Basan
Opis: [EN]PUSH-PULL HOE 270 MM YELLOW 1 * 1 SZT
j.m.: 1 * 1 SZT


Numer katalogowy: (BSNC59004)
Producent: Basan
Opis: [EN]PUSH-PULL HOE 270 MM RED 1 * 1 SZT
j.m.: 1 * 1 SZT


Numer katalogowy: (BSNC59005)
Producent: Basan
Opis: [EN]PUSH-PULL HOE 270 MM WHITE 1 * 1 SZT
j.m.: 1 * 1 SZT


Numer katalogowy: (40047.)
Producent: Biotium
Opis: Hoechst dyes are cell membrane-permeant, minor groove-binding blue fluorescent DNA stains. Hoechst dyes are widely used in cell cycle and apoptosis studies and also as nuclear counterstains.
j.m.: 1 * 100 mg


Numer katalogowy: (ENZOENZ52401)
Producent: ENZO LIFE SCIENCES
Opis: DNA dye
j.m.: 1 * 100 mg


Numer katalogowy: (40046.)
Producent: Biotium
Opis: Hoechst dyes are cell membrane-permeant, minor groove-binding blue fluorescent DNA stains. Hoechst dyes are widely used in cell cycle and apoptosis studies and also as nuclear counterstains. Hoechst 33342 is reported to be slightly more membrane-permeable than Hoechst 33258, but either dye can be used to stain live or fixed cell in buffer or medium at 1 ug/mL, with no wash step required.
j.m.: 1 * 10 mL


Numer katalogowy: (ENZOENZ52402)
Producent: ENZO LIFE SCIENCES
Opis: DNA dye
j.m.: 1 * 100 mg


Numer katalogowy: (J62134.MC)
Producent: Thermo Fisher Scientific
Opis: bisBenzimide H-33342 trihydrochloride trihydrate (Hoechst 33342) 98%
j.m.: 1 * 100 mg

MSDS Certyfikaty


Numer katalogowy: (AATB17537)
Producent: AAT BIOQUEST
Opis: The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy.
j.m.: 1 * 5 mg


Numer katalogowy: (AATB17538)
Producent: AAT BIOQUEST
Opis: The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy.
j.m.: 1 * 100 µl


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