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Anti-EGFR5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-9813R-A680)

Producent: Bioss

Opis: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell Signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumour endothelium than in normal tissue endothelium, it is considered to be a candidate for tumour vascular targeting.

j.m.: 1 * 100 µl

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Anti-ATG9A Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-5199R-A350)

Producent: Bioss

Opis: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.

j.m.: 1 * 100 µl

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Anti-BMP8B Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-12873R-CY3)

Producent: Bioss

Opis: Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

j.m.: 1 * 100 µl

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Anti-BMP8B Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-12873R-CY7)

Producent: Bioss

j.m.: 1 * 100 µl

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Anti-NL1 Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-4212R-CY7)

Producent: Bioss

Opis: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses (By similarity).

j.m.: 1 * 100 µl

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Anti-COL4A1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-4595R-A350)

Producent: Bioss

Opis: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.

j.m.: 1 * 100 µl

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