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Image Unavailable-BOSSBS-11844R-A680

Anti-GEFT Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-11844R-A680)
Producent: Bioss
Opis: GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7789R

Anti-CHMP1B Rabbit Polyclonal Antibody

Numer katalogowy: (BOSSBS-7789R)
Producent: Bioss
Opis: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7789R-CY3

Anti-CHMP1B Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-7789R-CY3)
Producent: Bioss
Opis: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-12873R-A750

Anti-BMP8b Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numer katalogowy: (BOSSBS-12873R-A750)
Producent: Bioss
Opis: Bone morphogenic proteins (BMPs) are members of the TGF Beta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF Beta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-5919R-FITC

Anti-ANGPTL4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numer katalogowy: (BOSSBS-5919R-FITC)
Producent: Bioss
Opis: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
j.m.: 1 * 100 µl
Image Unavailable-SIALW257001-9KG-K

Hexyl formate, Sigma-Aldrich®

Producent: Merck
Opis: Hexyl formate, Sigma-Aldrich®

Image Unavailable-BOSSBS-2912R-CY3

Anti-MAP1A/MAP1B LC3 A/B Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-2912R-CY3)
Producent: Bioss
Opis: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7876R-A488

Anti-SPAG8 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-7876R-A488)
Producent: Bioss
Opis: May play a role in fertility and microtubule formation through interaction with RANBP9.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-7876R-HRP

Anti-SPAG8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-7876R-HRP)
Producent: Bioss
Opis: May play a role in fertility and microtubule formation through interaction with RANBP9.
j.m.: 1 * 100 µl
Image Unavailable-786-214

System usuwania detergentu, Detergent-OUT™ Tween®

Producent: G-Biosciences
Opis: DetergentOUT™ Tween® is a spin column format detergent removal resin for polysorbate or Tween® detergents or surfactants.

Certyfikaty

Image Unavailable-BIND7057-0005

Services for Ultra-Low Temperature Freezers, UF V Series

Numer katalogowy: (BIND7057-0005)
Producent: Binder
Opis: Qualification documents. Digital IQ/OQ/PQ documents in PDF format - supporting documents for validation performed by customers, according to customer requirements, PQ section added to qualification folder IQ/OQ; parameters: temperature, CO₂, O₂ - or pressure, depending on unit, Do: UF V
j.m.: 1 * 1 SZT
Image Unavailable-BOSSBS-5790R-A488

Anti-LOXL4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-5790R-A488)
Producent: Bioss
Opis: May modulate the formation of a collagenous extracellular matrix.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-6573R-A488

Anti-RPL5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-6573R-A488)
Producent: Bioss
Opis: Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-10200R-FITC

Anti-SOST Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numer katalogowy: (BOSSBS-10200R-FITC)
Producent: Bioss
Opis: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-6573R-A647

Anti-RPL5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-6573R-A647)
Producent: Bioss
Opis: Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-10200R-A488

Anti-SOST Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-10200R-A488)
Producent: Bioss
Opis: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
j.m.: 1 * 100 µl
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
Do zakupu tego produktu może być potrzebna dodatkowa dokumentacja. Przedstawiciel VWR skontaktuje się z Tobą w razie potrzeby.
Ten produkt jest zablokowany na stronie internetowej. W celu zamówienia, skontaktuj się z Działem Obsługi Klienta.
Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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