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Wyszukano: CL-82198+(MMP-13+inhibitor)


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Numer katalogowy: (BOSSBS-1286R-A488)
Producent: Bioss
Opis: Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-1286R-CY7)
Producent: Bioss
Opis: Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-1286R-A750)
Producent: Bioss
Opis: Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
j.m.: 1 * 100 µl


Producent: ENZO LIFE SCIENCES
Opis: The Screen-Well™ Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library includes inhibitors to a broad range of important proteases and is a convenient and cost-effective way to purchase a panel of protease inhibitors for chemical genomics, assay development, and other applications. It includes inhibitors of: Calpains, TPPII, Neutrophil Elastase, Cathepsins, DPPIV, Caspases, Granzyme B, gamma-Secretase, Furin, MMPs, ACE, Kallikrein, Proteasome, Aminopeptidase B, and many more.

New Product

Numer katalogowy: (ENZOBMLP2280100)
Producent: ENZO LIFE SCIENCES
Opis: Sensitive fluorogenic substrate for TACE (TNFalpha converting enzyme, ADAM17). Also cleaved by ADAM10 and likely other ADAMs and MMPs. The kcat/Km of TACE for this substrate is 7-fold higher than for the same peptide with the Mca-Dpa fluorophore-quencher pair. FAM fluorescence is quenched by the TAMRA group until cleavage separates them. Ex.: 485 nm, Em.: 535 nm, although the following Ex/Em can also be used: 490,494/515,520 nm. This substrate is useful for inhibitor screening, kinetic analysis, and cellular activity assay.
j.m.: 1 * 100 µG

New Product


Producent: MP Biomedicals
Opis: Ketoconazole is an antifungal agent; Cytochrome P450 inhibitor and demonstrates anti-psoriatic activity. A liver cytochrome responsible for the metabolism of many drug substrates in humans.

Numer katalogowy: (ENZOALX630069C500)
Producent: ENZO LIFE SCIENCES
Opis: Potent neurotoxin. Small conductance Cl⁻ channel blocker. Highly specific marker for glioma cells and tumors of neuroectodermal origin. Inhibits the activity of matrix metalloproteinase-2 (MMP-2).
j.m.: 1 * 500 µG

New Product


Numer katalogowy: (ENZOBMLSE4930010)
Producent: ENZO LIFE SCIENCES
Opis: Produced in insect cells. Primarily full length latent MMP-13, with some active forms present.
j.m.: 1 * 10 µG

New Product


Numer katalogowy: (ENZOBMLAK0140001)
Producent: ENZO LIFE SCIENCES
Opis: Enzyme regulation and kinetics, comparative studies of substrate or inhibitor specificities, cleavage of target proteins. Assay or digest conditions can vary widely, but concentrations for the MMP enzymes can range between 10 and 300 nM, or higher. Reaction temperatures can be between 25 and 37°C, and reaction times can range from 10 min to overnight, again depending on application and substrate. A typical assay buffer is 50 mM HEPES, pH 7,0, 10 mM CaCl₂, 0,05% Brij-35. For more information, contact Enzo Life Sciences Technical Support.
j.m.: 1 * 1 KIT

New Product


Numer katalogowy: (BWRLBS6668)
Producent: Bioworld Technology
Opis: Recombinant full length Human MMP-13.
j.m.: 1 * 100 µG


Numer katalogowy: (ENZOBMLSE2460010)
Producent: ENZO LIFE SCIENCES
Opis: Produced in <i>E. coli</i>. Active Matrix Metalloproteinase-13 (MMP-13, collagenase-3) catalytic domain from human cDNA.
j.m.: 1 * 10 µG

New Product


Numer katalogowy: (BWRLBS1231)
Producent: Bioworld Technology
Opis: Synthetic peptide, corresponding to amino acids N-terminus of Human MMP-13.
j.m.: 1 * 100 µG


Numer katalogowy: (BOSSBS-5859R)
Producent: Bioss
Opis: ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-0416R-CY5.5)
Producent: Bioss
Opis: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-1, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-0416R-HRP)
Producent: Bioss
Opis: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-1, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-0416R-CY5)
Producent: Bioss
Opis: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-1, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
j.m.: 1 * 100 µl


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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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Produkt oryginalny został wycofany. Dostępny jest wskazny zamiennik .
Wybrany produkt został wycofany - sprzedaż do wyczerpania zapasów. Dostępne zamienniki można znaleźć poprzez wpisanie powyższego numeru katalogowego VWR w okno wyszukiwarki. Jeśli potrzebujesz dalszej pomocy, prosimy o kontakt z Działem Doradztwa Produktowego pod numerem telefonu 58 3238 220.
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