Wyszukano: Biosensis

Numer katalogowy: (BSENM-1744-50)

Producent: Biosensis

Opis: BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.

j.m.: 1 * 50 µG

Wyprzedaż

Numer katalogowy: (BSENR-1838-100)

Producent: Biosensis

Opis: The green fluorescent protein (GFP) is a 27 kDa protein isolated originally from the jellyfish Aequoria victoria. It has an endogenous fluorochrome activity with excitation maximum at 395nm and emission maximum at 509 nm, which is similar to that of fluorescein. GFP can be expressed in fluorescent form in essentially any prokaryotic or eukaryotic cell.
This GFP rabbit antibody was made against a recombinant GFP construct originating from an Aequoria species which was engineered to improve spectral properties and prevent oligomerization (1). This form of GFP, referred to as AcGFP, is 94% identical to the eGFP developed by Tsien and co-workers. The antibody can be used to verify the expression, size and stability of both AcGFP and eGFP fusion proteins in western blotting experiments and to amplify GFP signals in tissues of transgenic animals.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSENM-1692-100)

Producent: Biosensis

Opis: Anti-HSPB1 Mouse T4 Antibody [clone: 6H11]

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSENM-1249-100)

Producent: Biosensis

Opis: X63 is a control mouse IgG antibody with no known reactivity. The antibody has been used successfully a negative control in westerns, all forms of IHC, IP and FACS

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSENR-1556-100)

Producent: Biosensis

Opis: The elF2c (Argonaute, Ago) protein is a core protein of the RNA-induced silencing complex (RISC).

j.m.: 1 * 100 µl

Wyprzedaż

Numer katalogowy: (BSENM-1797-100)

Producent: Biosensis

Opis: Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Ref: uniprot.org

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSENC-1807-50)

Producent: Biosensis

Opis: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). Ref: uniprot.org

j.m.: 1 * 50 µl

Wyprzedaż

Numer katalogowy: (BSENBEK-2237-1P)

Producent: Biosensis

Opis: The Biosensis proBDNF (Brain-derived neurotrophic factor, BDNF, Abrineurin) RapidTM enzyme-linked immunosorbent assay (ELISA) Kit is a sandwich ELISA that allows the specific, fast and reliable quantification of proBDNF in less than 4 hours in cell culture supernatants, human serum and EDTA-plasma only if used as directed. Please refer to the kit protocol for specific use instructions for each substrate application, in particular human blood samples.

j.m.: 1 * 1 KIT

Wyprzedaż

Numer katalogowy: (BSENPE-1750-1000)

Producent: Biosensis

Opis: A proprietary preparation of human amyloid beta peptide (amino acids 1-42) that was initially monomerized by HFIP-treatment and then allowed to form oligomers by the procedure described in Youmans KL et al., 2012, followed by lyophilisation using Biosensis’ proprietary stabilization procedures.

The resulting oligomeric mixture has been specially designed to allow the formation of stable, oligomeric Aβ1-42 peptide, multimeric complexes or oligomers. The material is intended to be used as a stable and consistent standard or positive control for oligomeric ELISA assays, as well as other research applications. This product is supplied as 2 x 500 ng vials, each containing lyophilized Aβ oligomers. Note that the amount of provided oligomeric protein is based on the amount of monomeric Aβ used to form these oligomers. The precise formation, size and number of oligomers cannot be quantified by any known method.

j.m.: 1 * 1 µG

Wyprzedaż

Numer katalogowy: (BSENS-1759-100)

Producent: Biosensis

Opis: Sheep serum was obtained from non-immunised animals. This whole serum can be used as negative control antibody for various immunological techniques where sheep primary antibodies (whole serum) are used.

j.m.: 1 * 100 µl

Wyprzedaż

Producent: Biosensis

Opis: The Neurotrophin Antibody Kit contains a collection of sheep antibodies raised against BDNF, NGF, NT3 and NT4/5. The kit is completed with one vial of normal sheep IgG for use as negative control. This kit presents a cost-effective way to investigate neurotrophin protein expression and function by immunological techniques such as immunohistochemistry, ELISA, and inhibition of biological activity.

Numer katalogowy: (BSENM-1648-100)

Producent: Biosensis

Opis: Anti-DCX Mouse T4 Antibody [clone: 30]

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSENG-1784-100)

Producent: Biosensis

Opis: Apolipoprotein E (ApoE) is a lipoprotein involved in fat metabolism and acts as cholesterol carrier between cells and across tissues. On a genetic level, three APOE alleles are described, APOE2, APOE3 and APOE4. These alleles give rise to six APOE isoforms, which are differentially implicated in various diseases. In the peripheral system, APOE4 is linked to increased risk of atherosclerosis. In the CNS, the ability of APOE4 in clearing beta-amyloid is impaired, while APOE3 and APOE2 are more efficient in performing this task. The APOE4 genotype in particular has been linked to increased risk for developing Alzheimer's Disease.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSENM-1813-100)

Producent: Biosensis

Opis: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Ref: uniprot.org. Antibody is specific for parvalbumin and does not recognize closely related proteins calretinin and calbindin as determined by Western Blotting.

j.m.: 1 * 100 µG

Wyprzedaż

Numer katalogowy: (BSENC-1798-50)

Producent: Biosensis

Opis: Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Ref: uniprot.org. Antibody is specific for calbindin and does not recognize closely related proteins parvalbumin and calretinin as determined by Western Blotting.

j.m.: 1 * 50 µl

Wyprzedaż

Numer katalogowy: (BSENM-1656-100)

Producent: Biosensis

Opis: Anti-UBQL2 Mouse T4 Antibody [clone: 6H9]

j.m.: 1 * 100 µG

Wyprzedaż