Wyszukano: Biosensis

Producent: Biosensis

Opis: The Biosensis proBDNF Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the specific, fast and reliable quantification of proBDNF in less than 4 hours in cell culture supernatants, cell lysates, serum, citrate-plasma and tissue extracts only if used as directed.

Numer katalogowy: (BSENM-1802-50)

Producent: Biosensis

Opis: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Ref: uniprot.org

j.m.: 1 * 50 µG

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Producent: Biosensis

Opis: MC192-saporin is an antibody conjugate comprising of the monoclonal antibody MC192 against rat p75NTR, the nerve growth factor receptor, chemically conjugated via a reducible disulfide bridge to the ribosome-inactivating protein saporin, purified from saponaria officinalis.

Numer katalogowy: (BSENR-1794-100)

Producent: Biosensis

Opis: Beta-casein has an important role in determination of the surface properties of the casein micelles. it is cleaved into 3 chains (casoparan, casohypotensin and antioxidant peptide). Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide and induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity.

j.m.: 1 * 100 µl

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Numer katalogowy: (BSENM-1763-100-FT)

Producent: Biosensis

Opis: Mouse monoclonal antibody (Clone X63) with no known antigen binding ability was purified from hybridoma cell culture medium by Protein G chromatography and labelled with FITC. X63-FITC is useful as a negative control antibody for immunofluorescence studies using FITC-labelled primary antibodies.

j.m.: 1 * 100 µl

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Numer katalogowy: (BSENBEK-2240-2P)

Producent: Biosensis

Opis: The Biosensis Mature BDNF/proBDNF Combo RapidTM enzyme-linked immunosorbent assay (ELISA) Kit combines individual, but complementary ELISA kits for the two most important BDNF isoforms: Mature BDNF (BSENBEK-2211) and full-length proBDNF (BSENBEK-2217).

j.m.: 1 * 192 Tests

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Numer katalogowy: (BSENR-1717-50)

Producent: Biosensis

Opis: Anti-TrkB (phospho Y816/Y817) Rabbit Polyclonal Antibody

j.m.: 1 * 50 µG

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Numer katalogowy: (BSENTR-150-FJB)

Producent: Biosensis

Opis: The causes and effects of neuronal degeneration are of major interest to a wide variety of neuroscientists. Paralleling this growing interest is an increasing number of methods applicable to the detection of neuronal degeneration. The fluorescent dye Fluoro-Jade® B (FJB), like its more purified brother Fluoro-Jade® C (FJC), is an anionic fluorescein derivative useful for the histological staining of neurons undergoing degeneration.

j.m.: 1 * 30 mg

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Numer katalogowy: (BSENM-1689-100)

Producent: Biosensis

Opis: Anti-LMNA Mouse T4 Antibody [clone: 4C4]

j.m.: 1 * 100 µG

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Numer katalogowy: (BSENM-1646-100)

Producent: Biosensis

Opis: Anti-ACTA Mouse T4 Antibody [clone: 5J11]

j.m.: 1 * 100 µG

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Numer katalogowy: (BSENM-027-50-AT)

Producent: Biosensis

Opis: Anti-TNR16 Mouse Monoclonal Antibody [clone: Clone: Me20.4] (Atto 488)

j.m.: 1 * 50 µG

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Numer katalogowy: (BSENM-1727-100)

Producent: Biosensis

Opis: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake (Ref: uniprot.org). ProGDNF is the unprocessed precursor molecule of mature GDNF and exists as homodimer.

j.m.: 1 * 100 µG

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Numer katalogowy: (BSENTR-300-AG)

Producent: Biosensis

Opis: Amylo-Glo RTD reagent is designed to stain amyloid plaques in tissue sections.

j.m.: 1 * 1 KIT

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Numer katalogowy: (BSENR-1651-100)

Producent: Biosensis

Opis: GAP43 is very abundant protein which is found concentrated in neurons. One group discovered it as one of three proteins which becomes unregulated during the regeneration of the toad optic nerve (1). Three GAPs (Growth associated proteins) were discovered, and the number 43 comes from the apparent SDS-PAGE molecular weight of the one named GAP43. The HGNC name for this protein is, not surprisingly, GAP43. Later work showed that GAP43 does not run on SDS-PAGE in a fashion which accurately reflects its molecular weight, and that GAP43 proteins from different species may run at different apparent molecular weights. Partly due to these features GAP43 were independently discovered by several different groups and therefore has several alternate names, such as protein F1, pp46, neuromodulin, neural phosphoprotein B-50 and calmodulin-binding protein P-57. In each case the number reflects the apparent SDS-PAGE molecular weight, and underlines the unusual properties of this molecule. Mammalian GAP43 proteins contains only 226-243 amino acids, and so the real molecular weight is 23.61-25.14 kDa. GAP43 has been extensively studied and is known to be a major protein kinase C substrate and to bind calmodulin avidly. GAP43 is anchored to the plasma membrane by palmitoylation modifications.

j.m.: 1 * 100 µG

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Numer katalogowy: (BSENR-1381-100)

Producent: Biosensis

Opis: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. MMP2 isoform 2 mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways. Catalytic activity of MMP2 causes cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln. (Ref: uniprot.org).

j.m.: 1 * 100 µG

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Numer katalogowy: (BSENR-138-500)

Producent: Biosensis

Opis: FUNCTION: Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. FUNCTION: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. SUBCELLULAR LOCATION: Cytoplasm. Colocalizes with nonmuscle actin. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells. INDUCTION: By apoptotic stimuli. PTM: Conjugated to ATG12; which is essential for autophagy, but is not required for association with isolation membrane. SIMILARITY: Belongs to the ATG5 family.

j.m.: 1 * 500 µG

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