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Image Unavailable-BOSSBS-11040R-CY5

Anti-REG3A Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-11040R-CY5)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11040R-CY3

Anti-REG3A Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-11040R-CY3)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11040R-A350

Anti-REG3A Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numer katalogowy: (BOSSBS-11040R-A350)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11040R-A488

Anti-REG3A Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numer katalogowy: (BOSSBS-11040R-A488)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11040R-HRP

Anti-REG3A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numer katalogowy: (BOSSBS-11040R-HRP)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11040R-A647

Anti-REG3A Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numer katalogowy: (BOSSBS-11040R-A647)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11040R-A680

Anti-Bestrophin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-11040R-A680)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11040R-CY7

Anti-REG3A Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-11040R-CY7)
Producent: Bioss
Opis: Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
j.m.: 1 * 100 µl
Image Unavailable-216585-500G

Amberlite® IRA-900 (Cl), ca. 60% moisture ion-exchange resin, Supelco®

Numer katalogowy: (216585-500G)
Producent: Merck
Opis: Amberlite® IRA-900 chloride form is a macroporous, polystyrenic type 1 resin.[1] This resin was found to catalyze the photodecomposition of carbon tetrachloride in ethanol.
j.m.: 1 * 500 g

Certyfikaty


Image Unavailable-BOSSBS-11041R-CY5

Anti-BEST2 Rabbit Polyclonal Antibody (Cy5®)

Numer katalogowy: (BOSSBS-11041R-CY5)
Producent: Bioss
Opis: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
j.m.: 1 * 100 µl
Image Unavailable-SPCMSO155-500GM

chlorek sodu

Numer katalogowy: (SPCMSO155-500GM)
Producent: Spectrum Chemical
Opis: Sodium Chloride, Granular, USP is used in a variety of pharmaceutical formulations, to produce isotonic formulations, in tablet formulations and as an osmotic agent. This product is not sterile and not intended for use in the manufacture of injectable dosage forms, peritoneal dialysis solutions, hemodialysis solutions or hemofiltration solutions.
j.m.: 1 * 500 g
Image Unavailable-ICNA0219005325

β-Cyklodekstryna, white powder

Producent: MP Biomedicals
Opis: β-cyclodextrin is most commonly used as a complexing agent. It is reported to be useful for the selective precipitation of enantiomeric, positional or structural isomers. It also forms a water soluble complex with dansyl chloride for fluorescent labeling of proteins.

Image Unavailable-BOSSBS-11041R-CY7

Anti-BEST2 Rabbit Polyclonal Antibody (Cy7®)

Numer katalogowy: (BOSSBS-11041R-CY7)
Producent: Bioss
Opis: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11041R-CY3

Anti-BEST2 Rabbit Polyclonal Antibody (Cy3®)

Numer katalogowy: (BOSSBS-11041R-CY3)
Producent: Bioss
Opis: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
j.m.: 1 * 100 µl
Image Unavailable-BOSSBS-11041R-A680

Anti-Bestrophin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numer katalogowy: (BOSSBS-11041R-A680)
Producent: Bioss
Opis: The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterised channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
j.m.: 1 * 100 µl
Image Unavailable-PRSI92-188

Human recombinant CLIC3 (from E. coli)

Numer katalogowy: (PRSI92-188)
Producent: ProSci Inc.
Opis: Chloride intracellular channel protein 3 (CLIC3) is encoded by the CLIC3 gene. CLIC3 is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain and one GST N-terminal domain. Chloride intracellular channel protein 3 high expressed in the placental, lung and heart, low expressed in skeletal muscle, kidney and pancreas. Chloride intracellular channel protein 3 can insert into membranes and forms chloride ion channels, may participate in cellular growth control.
j.m.: 1 * 50 µG
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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
Ten produkt jest ograniczony w dostępie i można go zamówić tylko przy użyciu zaaprobowanego konta. Jeśli potrzebujesz pomocy, napisz do Działu Prawnego VWR na tomasz.chrobak@pl.vwr.com
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