Wyszukano: Aflatoxin+B1

Numer katalogowy: (BOSSBS-9077R)

Producent: Bioss

Opis: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Specifically, Cdk2 interacts with Cyclins A, B1, B3, D, or E to control cell cycle progression. The Cyclin-dependent kinase 2-interacting protein (CINP) interacts with components of the replication complex and Cdk2 and Cdc7, thereby providing a functional and physical link between Cdk2 and Cdc7 during firing of the origins of replication. However, CINP is phopshorylated by Cdc7, but not by Cdk2. CINP also interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress and G2 checkpoint integrity.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-10138R-A750)

Producent: Bioss

Opis: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional Signalling into neighboring cells. The Signalling pathway downstream of the receptor is referred to as forward Signalling while the Signalling pathway downstream of the ephrin ligand is referred to as reverse Signalling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK Signalling cascades to regulate cell migration and adhesion respectively.

j.m.: 1 * 100 µl

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Numer katalogowy: (BNUM0680-50)

Producent: Biotium

Opis: This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.

j.m.: 1 * 50 µl

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Numer katalogowy: (BOSSBS-10139R-FITC)

Producent: Bioss

Opis: EphB1, previously known as Elk (eph like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class. EphB1 is expressed predominately in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, EphB1 signals regulation of cell attachment and cell to cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.

j.m.: 1 * 100 µl

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Producent: Thermo Fisher Scientific

Opis: Thiamine nitrate

MSDS Certyfikaty

Numer katalogowy: (PRSI24-099)

Producent: ProSci Inc.

Opis: Anti-NIP Recombinant Antibody [Clone: B1-8]

j.m.: 1 * 0,2 mg

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Numer katalogowy: (PRSI24-101)

Producent: ProSci Inc.

Opis: Anti-NIP Recombinant Antibody [Clone: B1-8]

j.m.: 1 * 0,2 mg

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Numer katalogowy: (ANTIA82838-100)

Producent: ANTIBODIES.COM

Opis: Goat polyclonal antibody to Lamin B1 for ELISA and WB with samples derived from human and mouse.

j.m.: 1 * 100 µG

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Numer katalogowy: (BOSSBS-12880R-A680)

Producent: Bioss

Opis: Spermatogenesis represents the intricate developmental process of mitotic and meiotic cell divisions that ultimately leads to the production of haploid spermatozoa. BOULE, a member of the human deleted in azoospermia (DAZ) family, functions as a key conserved switch that regulates the progression of germ cells through meiosis in man. BOULE is an RNA-binding protein that regulates the expression of twine, a Cdc25 phosphatase, which promotes progression through meiosis. BOULE is expressed not only in the testis, but also in the nervous system, where it may play a role in neural communication. Mutations in the BOULE gene are be associated with male infertility, and the relative proportions of the three BOULE isoforms (B1, B2 and B3) may function as predictive markers for meiotic efficiency.

j.m.: 1 * 100 µl

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Numer katalogowy: (730-0188)

Producent: THERMO OWL SCIENTIFIC

Opis: The durable, easy‑to‑use, Owl™ B1 EasyCast™ mini horizontal gel system is suitable for running between five and 28 samples and is ideal for most teaching applications.

j.m.: 1 * 1 SZT

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Producent: Spectrum Chemical

Opis: Thiamine Mononitrate, USP is the mononitrate salt form of a material also known as vitamin B1.

Numer katalogowy: (ANTIA86344-100)

Producent: ANTIBODIES.COM

Opis: Mouse monoclonal [B1] antibody to TCR gamma + TCR delta for Flow Cytometry, IHC-P and IHC-Fr with samples derived from Human and Non-Human Primates.

j.m.: 1 * 100 µG

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Numer katalogowy: (ANTIA93469-100)

Producent: ANTIBODIES.COM

Opis: Rabbit polyclonal antibody to Cyclin B1 (phospho Ser147) for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.

j.m.: 1 * 100 µG

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Numer katalogowy: (BOSSBS-11155R-A680)

Producent: Bioss

Opis: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protocadherein gamma cluster consists of three subfamilies (A, B and C). As a member of the gamma subfamily B, PCDHGB1 (Protocadherin gamma B1) is a 927 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. Typical of gamma protocadherins, PCDHGB1 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system. With localisation to synapses, members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGB1 that are produced as a result of alternative splicing events.

j.m.: 1 * 100 µl

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Numer katalogowy: (BOSSBS-11246R)

Producent: Bioss

Opis: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.

j.m.: 1 * 100 µl

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Numer katalogowy: (ABNOMAB13407)

Producent: Abnova

Opis: Mouse monoclonal antibody raised against native human CD45RB.

j.m.: 1 * 100 µG

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