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Numer katalogowy: (BOSSBS-12880R-CY5)
Producent: Bioss
Opis: Spermatogenesis represents the intricate developmental process of mitotic and meiotic cell divisions that ultimately leads to the production of haploid spermatozoa. BOULE, a member of the human deleted in azoospermia (DAZ) family, functions as a key conserved switch that regulates the progression of germ cells through meiosis in man. BOULE is an RNA-binding protein that regulates the expression of twine, a Cdc25 phosphatase, which promotes progression through meiosis. BOULE is expressed not only in the testis, but also in the nervous system, where it may play a role in neural communication. Mutations in the BOULE gene are be associated with male infertility, and the relative proportions of the three BOULE isoforms (B1, B2 and B3) may function as predictive markers for meiotic efficiency.
j.m.: 1 * 100 µl


Numer katalogowy: (ANTIA253641-100)
Producent: ANTIBODIES.COM
Opis: Mouse monoclonal [SPM619] antibody to Cyclin B1 for Flow Cytometry, IF and IHC-P with samples derived from human and mouse.
j.m.: 1 * 100 µG

New Product


Numer katalogowy: (ANTIA250461-100)
Producent: ANTIBODIES.COM
Opis: Mouse monoclonal [SPM619] antibody to Cyclin B1 for Flow Cytometry, IF and IHC-P with samples derived from Human and Mouse.
j.m.: 1 * 100 µG

New Product


Numer katalogowy: (ANTIA82838-100)
Producent: ANTIBODIES.COM
Opis: Goat polyclonal antibody to Lamin B1 for ELISA and WB with samples derived from human and mouse.
j.m.: 1 * 100 µG

New Product


Numer katalogowy: (PRSI24-102)
Producent: ProSci Inc.
Opis: Anti-NIP Recombinant Antibody [Clone: B1-8]
j.m.: 1 * 0,2 mg

New Product


Numer katalogowy: (PRSI24-104)
Producent: ProSci Inc.
Opis: Anti-NIP Recombinant Antibody [Clone: B1-8]
j.m.: 1 * 0,2 mg

New Product


Numer katalogowy: (BSBTPA1048)
Producent: Boster Bio
Opis: Rabbit IgG polyclonal antibody for Lamin-B1 (LMNB1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human;Rat.
j.m.: 1 * 0,1 mg


Numer katalogowy: (BOSSBS-6050R-A488)
Producent: Bioss
Opis: TSC-36 is a secreted extracellular glycoprotein. The amino acid sequence of TSC-36 is similar to follistatin, an inhibitor of activin, as it contains a follistatin module. TSC-36 is a heparin-binding protein suggested to have a role in the negative regulation of cellular growth, as its expression is induced in response to TGF-b1. In addition, TSC-36 is not found in small cell lung cancer (SCLC) cells, a highly aggressive neoplasm, but is detected in some non-small cell lung cancer (NSCLC) cells, a moderately aggressive neoplasm.. May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-12880R-CY3)
Producent: Bioss
Opis: Spermatogenesis represents the intricate developmental process of mitotic and meiotic cell divisions that ultimately leads to the production of haploid spermatozoa. BOULE, a member of the human deleted in azoospermia (DAZ) family, functions as a key conserved switch that regulates the progression of germ cells through meiosis in man. BOULE is an RNA-binding protein that regulates the expression of twine, a Cdc25 phosphatase, which promotes progression through meiosis. BOULE is expressed not only in the testis, but also in the nervous system, where it may play a role in neural communication. Mutations in the BOULE gene are be associated with male infertility, and the relative proportions of the three BOULE isoforms (B1, B2 and B3) may function as predictive markers for meiotic efficiency.
j.m.: 1 * 100 µl


Numer katalogowy: (BOSSBS-10138R-A680)
Producent: Bioss
Opis: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional Signalling into neighboring cells. The Signalling pathway downstream of the receptor is referred to as forward Signalling while the Signalling pathway downstream of the ephrin ligand is referred to as reverse Signalling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK Signalling cascades to regulate cell migration and adhesion respectively.
j.m.: 1 * 100 µl


Numer katalogowy: (ABNORAB01649.100UL)
Producent: Abnova
Opis: Anti-Cyclin B1 Rabbit Recombinant Antibody [clone: R08-9B7]
j.m.: 1 * 100 µl


Producent: Biotium
Opis: This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.

Producent: Biotium
Opis: This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.

Numer katalogowy: (BNUM1098-50)
Producent: Biotium
Opis: This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.
j.m.: 1 * 50 µl


Numer katalogowy: (BOSSBS-10139R-A647)
Producent: Bioss
Opis: EphB1, previously known as Elk (eph like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class. EphB1 is expressed predominately in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, EphB1 signals regulation of cell attachment and cell to cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
j.m.: 1 * 100 µl


Numer katalogowy: (ABNOMAB13407)
Producent: Abnova
Opis: Mouse monoclonal antibody raised against native human CD45RB.
j.m.: 1 * 100 µG


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Zapasy tego artykułu są ograniczone, ale możliwe, że jest on dostępny w pobliskim magazynie. Upewnij się, że jesteś zalogowany na stronie, aby móc sprawdzić dostępność zapasów. Jeśli call ciągle się wyświetla i potrzebujesz pomocy, zadzwoń na 58 323 82 00.
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